Biotechnology and pharmacological evaluation of Indian vegetable crop Lagenaria siceraria: an overview

• Published in: Applied microbiology and biotechnology Vol. 100; no. 3; pp. 1153 - 1162
• Main Authors: Roopan, Selvaraj Mohana, Devi Rajeswari, V, Kalpana, V. N, Elango, G
• Format: Journal Article
• Language: English
• Published: Berlin/Heidelberg Springer Berlin Heidelberg 01.02.2016; Springer; Springer Nature B.V
• Subjects: Agricultural biotechnology; Amino acids; ascorbic acid; beta-carotene; Biomass energy; Biomedical and Life Sciences; Biosensors; Biotechnology; chemical composition; Crop diseases; Cucurbita - chemistry; Cucurbita - classification; Cucurbitaceae; death; Dietary minerals; Diuretics; Enzymes; Ethnobotany; Flowers & plants; Fruits; Functional foods & nutraceuticals; Health aspects; heart; Humans; India; industrialization; Lagenaria siceraria; Life Sciences; Microbial Genetics and Genomics; Microbiology; minerals; Mini-Review; Nanoparticles; Nanotechnology; Organic chemicals; pectins; Plant Extracts - chemistry; Plant Extracts - pharmacology; plant growth substances; Proteomics; Seeds; Studies; urbanization; vegetable crops; Vegetables; Vegetables - chemistry; Vegetables - classification; vitamin B complex; India; Ethnobotanical uses; Proteomic analysis; Biodiesel production; Pharmacological activity; Lagenaria siceraria
• ISSN: 0175-7598; 1432-0614
• DOI: 10.1007/s00253-015-7190-0

Bottle gourd (Lagenaria siceraria) belongs to the family Cucurbitaceae, which comprises about 118 genera and 825 species. It is an important vegetable crop of India, and its production is influenced by a number of factors viz., environmental, nutritional, cultural operation and use of plant growth regulators. Since, bottle gourd belongs to a medicinal family, it plays a major role in the treatment of several diseases related to the skin and heart. There are several organic chemical compounds including vitamin B complex, pectin, dietary soluble fibres, ascorbic acid, beta-carotene, amino acids and minerals which have been isolated from this species. Therefore, the bottle gourd is considered to have a great impact on therapeutic health benefits. Due to drastic industrialization and urbanization, most of the human beings are facing several ill effects which may lead to death at extreme cases. Hence, the major research area was said to be nanotechnology. Taking into consideration, we have combined nanotechnology field with waste source in the name of green synthesis and planned to cure several diseases, as most of the researchers focused their work on this and succeeded too. The present study is a complete review of L. siceraria that covers the ethnomedical uses, chemical constituents, and pharmacological profile. This study is mainly focused on the antibacterial, hepatoprotective, diuretic and anthelminthic activities.