Impact of the COVID-19 pandemic on pediatric and adolescent vaccinations and well child visits in the United States: A database analysis

• Published in: Vaccine Vol. 40; no. 5; pp. 706 - 713
• Main Authors: Kujawski, Stephanie A., Yao, Lixia, Wang, H. Echo, Carias, Cristina, Chen, Ya-Ting
• Format: Journal Article
• Language: English
• Published: Netherlands Elsevier Ltd 31.01.2022; Elsevier Limited; The Authors. Published by Elsevier Ltd
• Subjects: Adolescent; Adolescents; Age; Age groups; Allergy and Immunology; Child; Child, Preschool; Children; Children & youth; Coronaviruses; COVID-19; COVID-19 infection; COVID-19 vaccines; Cross-Sectional Studies; Disease control; Electronic health records; Electronic medical records; Health care; health services; Hepatitis B; Human papillomavirus; Humans; Immunization; Infant; Infant, Newborn; Infectious disease; Measles; Morbidity; Outbreaks; Pandemics; Pediatrics; Rotavirus; SARS-CoV-2; Teenagers; Tetanus; United States - epidemiology; Vaccination; Vaccination coverage; Vaccines; Viral diseases; Viruses; Well-child visits; Whooping cough; United States; United States > US; COVID-19; Infectious disease; Pediatrics; Well-child visits; Vaccination coverage; Adolescents
• ISSN: 0264-410X; 1873-2518; 1873-2518
• DOI: 10.1016/j.vaccine.2021.12.064

The COVID-19 pandemic has disrupted healthcare, including immunization practice and well child visit attendance. Maintaining vaccination coverage is important to prevent disease outbreaks and morbidity. We assessed the impact of the COVID-19 pandemic on pediatric and adolescent vaccination administration and well child visit attendance in the United States. This cross-sectional study used IBM MarketScan Commercial Database (IMC) with Early View (healthcare claims database) and TriNetX Dataworks Global Network (electronic medical records database) from January 2018–March 2021. Individuals ≤ 18 years of age who were enrolled during the analysis month of interest (IMC with Early View) or had ≥ 1 health encounter at a participating institution (TriNetX Dataworks) were included. We calculated the monthly percent difference between well child visit attendance and vaccine administration rates for 10 recommended pediatric/adolescent vaccines in 2020 and 2021 compared with 2018–2019. Data were stratified by the age groups 0–2 years, 4–6 years, and 9–16 years. In IMC with Early View, the average monthly enrollment for children 0–18 years of age was 5.2 million. In TriNetX Dataworks, 12.2 million eligible individuals were included. Well child visits and vaccinations reached the lowest point in April 2020 compared with 2018–2019. Well child visit attendance and vaccine administration rates were inversely related to age, with initial reductions highest for adolescents and lowest for ages 0–2 years. Rates rebounded in June and September 2020 and stabilized to pre-pandemic levels in Fall 2020. Rates dropped below baseline in early 2021 for groups 0–2 years and 4–6 years. We found substantial disruptions in well child visit attendance and vaccination administration for children and adolescents during the COVID-19 pandemic in 2020 and early 2021. Continued efforts are needed to monitor recovery and catch up to avoid outbreaks and morbidity associated with vaccine-preventable diseases.