Hemagglutination by a human rotavirus isolate as evidence for transmission of animal rotaviruses to humans

• Published in: Journal of Clinical Microbiology Vol. 30; no. 4; pp. 1011 - 1013
• Main Authors: Nakagomi, O. (Akita University School of Medicine, Akita), Mochizuki, M, Aboudy, Y, Shif, I, Silberstein, I, Nakagomi, T
• Format: Journal Article
• Language: English
• Published: Washington, DC American Society for Microbiology 01.04.1992
• Subjects: AGGLUTININE; AGLUTININAS; Animals; AVES DE CORRAL; Biological and medical sciences; COBAYA; COBAYE; ERITROCITOS; ERYTHROCYTE; GENERO HUMANO; GENRE HUMAIN; Hemagglutination; Hemagglutination Inhibition Tests; Human viral diseases; Humans; In Vitro Techniques; Infectious diseases; Medical sciences; OVIN; OVINOS; ROTAVIRUS; Rotavirus - classification; Rotavirus - immunology; Rotavirus - pathogenicity; Rotavirus Infections - transmission; Species Specificity; TRANSMISION DE ENFERMEDADES; TRANSMISSION DES MALADIES; Viral diseases; Viral diseases of the digestive system; VOLAILLE; ZOONOSE; ZOONOSIS; Human; Human rotavirus; Hemagglutination test; Diarrhea; Reoviridae; Infection; Virus; Viral disease; Digestive diseases; Transmission from animal to man; Duovirus; Child; Clinical isolate
• ISSN: 0095-1137; 1098-660X
• DOI: 10.1128/jcm.30.4.1011-1013.1992

Human rotavirus strain Ro1845, which was isolated in 1985 from an Israeli child with diarrhea, has a hemagglutinin that is capable of agglutinating erythrocytes from guinea pigs, sheep, chickens, and humans (group O). Hemagglutination was inhibited after incubation with hyperimmune sera or in the presence of glycophorin, the erythrocyte receptor for animal rotaviruses. These results suggest that Ro1845 is an animal rotavirus that infected a human child