Stimulation of Homologous Recombination through Targeted Cleavage by Chimeric Nucleases

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Published inMolecular and Cellular Biology Vol. 21; no. 1; pp. 289 - 297
Main Authors Bibikova, Marina, Carroll, Dana, Segal, David J., Trautman, Jonathan K., Smith, Jeff, Kim, Yang-Gyun, Chandrasegaran, Srinivasan
Format Journal Article
LanguageEnglish
Published United States American Society for Microbiology 01.01.2001
Taylor & Francis
Subjects
Animals
Binding Sites
Catalysis
Deoxyribonucleases, Type II Site-Specific - chemistry
Deoxyribonucleases, Type II Site-Specific - genetics
Deoxyribonucleases, Type II Site-Specific - metabolism
DNA - genetics
DNA - metabolism
DNA Dynamics and Chromosome Structure
Gene Targeting
Microinjections
Models, Molecular
Mutation - genetics
nuclease
Oocytes - metabolism
Protein Conformation
Recombinant Fusion Proteins - chemistry
Recombinant Fusion Proteins - genetics
Recombinant Fusion Proteins - metabolism
Recombination, Genetic - genetics
Sequence Homology, Nucleic Acid
Substrate Specificity
Xenopus
Xenopus laevis
zinc finger
Zinc Fingers
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Summary:Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit StumbleUpon Twitter current issue Spotlights in the Current Issue MCB About MCB Subscribers Authors Reviewers Advertisers Inquiries from the Press Permissions & Commercial Reprints ASM Journals Public Access Policy MCB RSS Feeds 1752 N Street N.W. • Washington DC 20036 202.737.3600 • 202.942.9355 fax • journals@asmusa.org Print ISSN: 0270-7306 Online ISSN: 1098-5549 Copyright © 2014 by the American Society for Microbiology.   For an alternate route to MCB .asm.org, visit: MCB       
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Present address: Department of Biology, Massachusetts Institute of Technology, Cambridge, MA 02139.
Corresponding author. Mailing address for Dana Carroll: Department of Biochemistry, University of Utah School of Medicine, Salt Lake City, UT 84132. Phone: (801) 581-5977. Fax: (801) 581-7959. E-mail: carroll@path.utah.edu. Mailing address for Srinivasan Chandrasegaran: Department of Environmental Health Sciences, The Johns Hopkins University School of Hygiene and Public Health, 615 N. Wolfe St., Baltimore, MD 21205. Phone: (410) 614-2289. Fax: (410) 955-0617. E-mail: chandra@welchlink.welch.jhu.edu.
Present address: Department of Molecular Biology, The Scripps Research Institute, La Jolla, CA 92037.
ISSN:0270-7306
1098-5549
1098-5549
DOI:10.1128/MCB.21.1.289-297.2001