Green tea suppresses D-galactosamine-induced liver injury in rats

• Published in: Bioscience, biotechnology, and biochemistry Vol. 62; no. 3; pp. 609 - 611
• Main Authors: Sugiyama, K. (Shizuoka Univ. (Japan). Faculty of Agriculture), He, P, Wada, S, Tamaki, F, Saeki, S
• Format: Journal Article
• Language: English
• Published: Tokyo Japan Society for Bioscience, Biotechnology, and Agrochemistry 01.03.1998; Japan Society for Bioscience Biotechnology and Agrochemistry; Oxford University Press
• Subjects: Alanine Transaminase - blood; AMINO SUGARS; AMINOAZUCARES; AMINOSUCRE; ANIMAL DE LABORATOIRE; ANIMALES DE LABORATORIO; Animals; Aspartate Aminotransferases - blood; Biological and medical sciences; CARBON TETRACHLORIDE; Carbon Tetrachloride - toxicity; Chemical and Drug Induced Liver Injury; D-galactosamine; Dietary Supplements; ENFERMEDADES HEPATICAS; EXTRACTOS; EXTRACTS; EXTRAIT; Feeding. Feeding behavior; Fundamental and applied biological sciences. Psychology; Galactosamine - toxicity; General pharmacology; green tea; LABORATORY ANIMALS; LIVER DISEASES; Liver Diseases - enzymology; Liver Diseases - prevention & control; liver injury; MALADIE DU FOIE; Male; Medical sciences; Pharmacognosy. Homeopathy. Health food; Pharmacology. Drug treatments; Plant Extracts - therapeutic use; RAT; RATA; RATS; Rats, Wistar; TEA; TETRACHLORURE DE CARBONE; TETRACLORURO DE CARBONO; THE; Vertebrates: anatomy and physiology, studies on body, several organs or systems; Galactosamine; Rat; Hepatoprotector; Pharmacognosy; Toxicity; Liver; Carbon tetrachloride; Rodentia; Biological activity; Medicinal plant; Prevention; In vivo; Vertebrata; Camellia sinensis; Mammalia; Dicotyledones; Animal; Angiospermae; Plant origin; Spermatophyta; Tea extract; Beverage; Green tea; Theaceae
• ISSN: 0916-8451; 1347-6947
• DOI: 10.1271/bbb.62.609

Dietary supplementation with powder of a green tea extract suppressed the enhancement of plasma alanine aminotransferase and aspartate aminotransferase activities induced by D-galactosamine, but not by carbon tetrachloride, in a dose-dependent manner in rats. The minimum does to cause a significant effect was 1 to 2%. Drinking green tea also suppressed plasma enzyme activities. These results indicate that green tea had a liver injury-preventive effect