Dietary phospholipid concentrate from bovine milk improves epidermal function in hairless mice

We investigated the effect of dietary phospholipid (PL) concentrate from bovine milk on the epidermis. Thirteen-week-old hairless male and female mice (Hos:HR-1) were separated into two experimental groups, each fed two experimental diets: the control group and the PL group. The mice were given the...

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Published inBioscience, biotechnology, and biochemistry Vol. 72; no. 8; pp. 2151 - 2157
Main Authors Haruta, Y.(Snow Brand Milk Products Co. Ltd., Kawagoe, Saitama (Japan). Technology and Research Inst.), Kato, K, Yoshioka, T
Format Journal Article
LanguageEnglish
Published Tokyo Japan Society for Bioscience, Biotechnology, and Agrochemistry 01.08.2008
Japan Society for Bioscience Biotechnology and Agrochemistry
Oxford University Press
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Summary:We investigated the effect of dietary phospholipid (PL) concentrate from bovine milk on the epidermis. Thirteen-week-old hairless male and female mice (Hos:HR-1) were separated into two experimental groups, each fed two experimental diets: the control group and the PL group. The mice were given the experimental diets for 6 weeks. Stratum corneum hydration and transepidermal water loss (TEWL) were measured using Corneometer CM825 and Tewameter TM300 (Courage and Khazaka Electronics, Cologne, Germany) at 3 weeks and 6 weeks. After the feeding period, ceramides in stratum corneum were analyzed. We found that stratum corneum hydration and ceramides in the PL group were significantly higher than those in the control group and that TEWL in the PL group tended to decrease. These results indicate that dietary PL concentrate improves epidermal function by increasing the amount of ceramides, resulting in higher hydration.
Bibliography:L51
2009000516
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ISSN:0916-8451
1347-6947
DOI:10.1271/bbb.80212