Function of Feline Signaling Lymphocyte Activation Molecule as a Receptor of Canine Distemper Virus

• Published in: Journal of Veterinary Medical Science Vol. 75; no. 8; pp. 1085 - 1089
• Main Authors: HARA, Yuka, SUZUKI, Junko, NOGUCHI, Keita, TERADA, Yutaka, SHIMODA, Hiroshi, MIZUNO, Takuya, MAEDA, Ken
• Format: Journal Article
• Language: English
• Published: Japan JAPANESE SOCIETY OF VETERINARY SCIENCE 2013; Japan Science and Technology Agency
• Subjects: Amino Acid Sequence; Animals; Antigens, CD - genetics; Antigens, CD - metabolism; Base Sequence; canine distemper virus; Cats; Cluster Analysis; Distemper Virus, Canine - physiology; DNA Primers - genetics; feline; Feline Panleukopenia - physiopathology; Feline Panleukopenia - virology; Flow Cytometry; Molecular Sequence Data; Phylogeny; Receptors, Cell Surface - genetics; Receptors, Cell Surface - metabolism; Receptors, Virus - metabolism; Sequence Analysis, DNA; signaling lymphocyte activation molecule; Signaling Lymphocytic Activation Molecule Family Member 1; Species Specificity; Virus Internalization

Morbilliviruses use signaling lymphocyte activation molecule (SLAM) as a receptor for their entry to cells. In this study, a complete gene encoding SLAM of a domestic cat was identified. The identity of feline SLAM with canine one was 73%, and feline SLAM formed the same cluster with those of carniv...