A functional classification of medial frontal negativity ERPs: Theta oscillations and single subject effects

• Published in: Psychophysiology Vol. 53; no. 9; pp. 1317 - 1334
• Main Authors: Van Noordt, Stefon J.R., Campopiano, Allan, Segalowitz, Sidney J.
• Format: Journal Article
• Language: English
• Published: United States Blackwell Publishing Ltd 01.09.2016
• Subjects: Adult; Classification; Electroencephalography; Evoked Potentials - physiology; Executive Function - physiology; Female; Frontal Lobe - physiology; Humans; Independent component analysis; Male; Medial frontal cortex; Neuropsychology; Performance monitoring; Psychomotor Performance - physiology; Robust estimation; Theta; Theta Rhythm - physiology; Young Adult; Robust estimation; Performance monitoring; Medial frontal cortex; Theta; Independent component analysis
• ISSN: 0048-5772; 1469-8986; 1469-8986; 1540-5958
• DOI: 10.1111/psyp.12689

Theta oscillations in the EEG have been linked to several ERPs that are elicited during performance‐monitoring tasks, including the error‐related negativity (ERN), no‐go N2, and the feedback‐related negativity (FRN). We used a novel paradigm to isolate independent components (ICs) in single subjects' (n = 27) EEG accounting for a medial frontal negativity (MFN) to response cue stimuli that signal a potential change in future response demands. Medial frontal projecting ICs that were sensitive to these response cues also described the ERNs, no‐go N2s, and, to a lesser extent, the FRNs, that were elicited in letter flanker, go/no‐go, and time‐estimation tasks, respectively. In addition, percentile bootstrap tests using trimmed means indicated that the medial frontal ICs show an increase in theta activity during the ERN, no‐go N2, and FRN across tasks and within individuals. Our results provide an important validation of previous studies by showing that increases in medial frontal theta to cognitively challenging events in multiple paradigms is a reliable effect within individuals and can be elicited by basic stimulus cues that signal the potential need to adjust response control. Thus, medial frontal theta reflects a neural response common to all MFN paradigms and characterizes the general process of controlling attention without the need to induce error commission, inhibited responses, or to present negative feedback.