CO 2 -Promoted and Copper-Catalyzed Dehydroxylative Coupling of Benzylic Alcohols by the NaBH 4 /I 2 System

An efficient and CO -promoted dehydroxylative coupling of benzylic alcohols catalyzed by ligand-free cuprous chloride has been achieved. The discovered catalytic reductive coupling reaction is a newly C-C bond-forming transformation of alcohols. Mechanistic insight is gained through control reaction...

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Bibliographic Details
Published inJournal of organic chemistry Vol. 89; no. 14; pp. 9810 - 9815
Main Authors Guo, Zhiqiang, Yang, Boru, Pang, Tengfei, Wei, Xuehong
Format Journal Article
LanguageEnglish
Published United States 19.07.2024
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Summary:An efficient and CO -promoted dehydroxylative coupling of benzylic alcohols catalyzed by ligand-free cuprous chloride has been achieved. The discovered catalytic reductive coupling reaction is a newly C-C bond-forming transformation of alcohols. Mechanistic insight is gained through control reactions.
ISSN:0022-3263
1520-6904
DOI:10.1021/acs.joc.4c00437