Regulation of Vegetative Phase Change in Arabidopsis thaliana by Cyclophilin 40

• Published in: Science (American Association for the Advancement of Science) Vol. 291; no. 5512; pp. 2405 - 2407
• Main Authors: Berardini, Tanya Z., Bollman, Krista, Sun, Hui, Poethig, R. Scott
• Format: Journal Article
• Language: English
• Published: Washington, DC American Society for the Advancement of Science 23.03.2001; American Association for the Advancement of Science; The American Association for the Advancement of Science
• Subjects: Agronomy. Soil science and plant productions; Alleles; Amino Acid Sequence; Arabidopsis - anatomy & histology; Arabidopsis - genetics; Arabidopsis - growth & development; Arabidopsis - physiology; Arabidopsis thaliana; Biological and medical sciences; Carrier Proteins - chemistry; Carrier Proteins - genetics; Carrier Proteins - physiology; Chromosome Mapping; cyclophilin 40; Cyclophilins; Cytoplasmic inheritance; Economic plant physiology; Exons; Flowers & plants; Fundamental and applied biological sciences. Psychology; Gene expression; Gene expression regulation; Gene Expression Regulation, Plant; Genes; Genes, Plant; Genetic mutation; Growth and development; Heat-Shock Proteins - genetics; Inflorescences; Leaves; Molecular Sequence Data; Morphogenesis, differentiation, rhizogenesis, tuberization. Senescence; Mutation; Peptidyl-Prolyl Isomerase F; Peptidylprolyl Isomerase - chemistry; Peptidylprolyl Isomerase - genetics; Peptidylprolyl Isomerase - physiology; Phenotype; Phenotypes; Phytochemistry; Plant biochemistry; Plant growth; Plant growth. Development of the storage organs; Plant Leaves - anatomy & histology; Plant Leaves - growth & development; Plant physiology and development; Plant Shoots - growth & development; Plant Shoots - physiology; Plants; Proteins; Reproduction; Seedlings; Sequence Alignment; SQUINT protein; Temperature; Trichomes; Vegetative apparatus, growth and morphogenesis. Senescence; United States; Peptidylprolyl isomerase; Enzyme; Inflorescence; Homology; Sexual reproduction; Genetic determinism; Structure function relationship; Arabidopsis thaliana; Phenotype; Isomerases; Gene; Cruciferae; Dicotyledones; Angiospermae; Development; Above ground plant part; Spermatophyta; Mutation; Experimental plant; cis-trans-Isomerases; Aminoacid sequence
• ISSN: 0036-8075; 1095-9203
• DOI: 10.1126/science.1057144

During its development, a plant shoot progresses from a juvenile to an adult phase of vegetative growth and from a reproductively incompetent to a reproductively competent state. In Arabidopsis, loss-of-function mutations in SQUINT (SQN) reduced the number of juvenile leaves and had subtle effects on inflorescence morphology but had no effect on flowering time or on reproductive competence. SQN encodes the Arabidopsis homolog of cyclophilin 40 (CyP40), a protein found in association with the Hsp90 chaperone complex in yeast, mammals, and plants. Thus, in Arabidopsis, CyP40 is specifically required for the vegetative but not the reproductive maturation of the shoot.