Effect of Extracts of Zingiberaceae Herbs on Gastric Secretion in Rabbits

Some of the Zingiberaceae herbs are known to be useful as stomachics. Water extracts and methanol extracts of eight such herbs were examined in intact unanesthetized rabbits for their effect n gastric secretion. Oral administration of either water extratcs or methanol extracts caused a significant d...

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Published inChemical & pharmaceutical bulletin Vol. 37; no. 1; pp. 215 - 217
Main Authors SAKAI, Kiyoshi, MIYAZAKI, Yohko, YAMANE, Toshiko, SAITOH, Yukiko, IKAWA, Chie, NISHIHATA, Toshiaki
Format Journal Article
LanguageEnglish
Published Tokyo The Pharmaceutical Society of Japan 01.01.1989
Maruzen
Japan Science and Technology Agency
Subjects
Animals
Biological and medical sciences
Gastric Juice - metabolism
Gastric Mucosa - drug effects
Gastric Mucosa - metabolism
General pharmacology
Male
Medical sciences
oral administration
Pharmacognosy. Homeopathy. Health food
Pharmacology. Drug treatments
Plant Extracts - pharmacology
Plants, Medicinal - analysis
Rabbits
Antiulcer agent
Plant origin
Medicinal plant
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Summary:Some of the Zingiberaceae herbs are known to be useful as stomachics. Water extracts and methanol extracts of eight such herbs were examined in intact unanesthetized rabbits for their effect n gastric secretion. Oral administration of either water extratcs or methanol extracts caused a significant decrease in gastric secretion. A significant effect of these extracts appeared at 3h after administration. The effect of water extracts on gastric secretion was very similar to that of cimetidine, with a significant decrease in acid output. The effect of the methanol extracts was primarily observed as decreased pepsin output.
Bibliography:ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 23
ISSN:0009-2363
1347-5223
DOI:10.1248/cpb.37.215