双相障碍共病肥胖的性别差异

双相障碍是情绪起伏不定、症状复杂多变的精神疾病.双相障碍患者代谢综合征患病率显著高于单相抑郁障碍和健康人群,且风险与抑郁严重程度及腹型肥胖有关.双相障碍共病肥胖存在性别差异,可能与童年不幸、偏头痛、激素水平改变、药物作用、饮食、生活方式等方面有关.文章从双相障碍临床特点及导致性别差异存在的可能机制进行综述....

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Bibliographic Details
Published in上海交通大学学报（医学版） Vol. 37; no. 12; pp. 1695 - 1698
Main Author 许晶晶;方贻儒
Format Journal Article
LanguageChinese
Published 上海交通大学 医学院附属精神卫生中心心境障碍科,上海,200030 2017
Subjects
代谢综合征
双相障碍
性别
肥胖
metabolic syndrome
肥胖
bipolar disorder
代谢综合征
gender
双相障碍
obesity
性别
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Summary:双相障碍是情绪起伏不定、症状复杂多变的精神疾病.双相障碍患者代谢综合征患病率显著高于单相抑郁障碍和健康人群,且风险与抑郁严重程度及腹型肥胖有关.双相障碍共病肥胖存在性别差异,可能与童年不幸、偏头痛、激素水平改变、药物作用、饮食、生活方式等方面有关.文章从双相障碍临床特点及导致性别差异存在的可能机制进行综述.
Bibliography:Bipolar disorder （BD） is a kind of psychiatric disorder with wildly alternating emotion and complicated symptoms. Subjects with BD had a significantly higher prevalence of metabolic syndrome when compared to subjects with major depressive disorder and non-psychiatric controls, with risk related to a higher depression score and abdominal obesity. Gender difference in the patients with BD and obesity may be related to childhood adversity, migraine, hormonal alterations, psychotropic medications, diet and lifestyle factors. This article reviewed clinical features and the potential mechanism of gender difference in bipolar disorder with comorbidity of obesity.
31-2045/R
XU Jing-jing, FANG Yi-ru （Division of Mood Disorders, Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine, Shanghai 200030, China）
bipolar disorder;obesity;gender;metabolic syndrome
ISSN:1674-8115
DOI:10.3969/j.issn.1674-8115.2017.12.022