Spontaneous intramedullary abscesses caused by Streptococcus anginosus: two case reports and review of the literature

• Published in: BMC infectious diseases Vol. 22; no. 1; p. 141
• Main Authors: Cerecedo-Lopez, Christian D, Bernstock, Joshua D, Dmytriw, Adam A, Chen, Jason A, Chalif, Joshua I, Gupta, Saksham, Driver, Joseph, Huang, Kevin, Stanley, Susan E, Li, Jonathan Z, Chi, John, Lu, Yi
• Format: Journal Article
• Language: English
• Published: England BioMed Central Ltd 10.02.2022; BioMed Central; BMC
• Subjects: Abdomen; Abscess; Abscess - diagnosis; Abscesses; Antibiotics; Care and treatment; Case Report; Case reports; Central nervous system diseases; Complications and side effects; Diagnosis; Edema; Glucose; Humans; Infections; Infectious diseases; Intramedullary; Literature reviews; Magnetic Resonance Imaging; Myelopathy; Neck pain; Paralysis; Proteins; Risk factors; Spinal cord; Spinal Cord Diseases - diagnostic imaging; Spinal Cord Diseases - drug therapy; Spine, spinal cord injury; Streptococcal infections; Streptococcus; Streptococcus anginosus; Suctioning; United States; Myelopathy; Streptococcus anginosus; Intramedullary; Abscess; Spine, spinal cord injury
• ISSN: 1471-2334; 1471-2334
• DOI: 10.1186/s12879-022-07099-7

Intramedullary abscesses are rare infections of the spinal cord. Intramedullary abscesses often have a complex presentation, making a high index of suspicion essential for prompt diagnosis and management. We present two cases of intramedullary abscesses referred to and ultimately managed at our institution. Delayed diagnosis occurred in both instances due to the rarity of intramedullary abscesses and their propensity to mimic other pathologies. For both patients, prompt surgical management and the rapid institution of broad-spectrum antibiotics were critical in preventing further neurological decline. Although rare, it is critical to consider intramedullary abscesses on the differential for any MRI lesions that are hyperintense on T2 and peripherally enhancing on T1 post-contrast sequences, as even short delays in treatment can lead to severe neurological damage.