Clinical characteristics and chest computed tomography findings related to the infectivity of pulmonary tuberculosis

• Published in: BMC infectious diseases Vol. 21; no. 1; p. 1197
• Main Authors: Wang, Yuanyuan, Shang, Xiaoqian, Wang, Liang, Fan, Jiahui, Tian, Fengming, Wang, Xuanzheng, Kong, Weina, Wang, Jing, Wang, Yunling, Ma, Xiumin
• Format: Journal Article
• Language: English
• Published: England BioMed Central Ltd 27.11.2021; BioMed Central; BMC
• Subjects: Acid-fast bacilli-negative; Acid-fast bacilli-positive; Bronchiectasis; Bronchostenosis; Calcification; Chest; Computed tomography; Consolidation; CT imaging; Diabetes; Diagnosis; Fever; Hemoptysis; Hospitals; Humans; Hyperhidrosis; Infections; Infectious diseases; Infectivity; Laboratories; Laboratory tests; Lung; Lymphadenopathy; Mycobacterium tuberculosis; Patients; Pulmonary tuberculosis; Retrospective Studies; Risk factors; Software; Sputum; Tomography; Tomography, X-Ray Computed; Tuberculosis; Tuberculosis, Pulmonary - diagnostic imaging; China; Acid-fast bacilli-positive; Pulmonary tuberculosis; Acid-fast bacilli-negative
• ISSN: 1471-2334; 1471-2334
• DOI: 10.1186/s12879-021-06901-2

This study mainly evaluates the clinical characteristics and chest chest computed tomography (CT) findings of AFB-positive and AFB-negative pulmonary tuberculosis (PTB) patients to explore the relationship between AFB-positive and clinico-radiological findings. A retrospective analysis of 224 hospitalized tuberculosis patients from 2018 to 2020 was undertaken. According to the AFB smear results, they were divided into AFB-positive pulmonary tuberculosis (positive by Ziehl-Neelsen staining) and AFB-negative pulmonary tuberculosis and patients' CT results and laboratory test results were analyzed. A total of 224 PTB patients were enrolled. AFB-positive (n = 94, 42%) and AFB-negative (n = 130, 58%). AFB-positive patients had more consolidation (77.7% vs. 53.8%, p < 0.01), cavity (55.3% vs. 34.6%, p < 0.01), calcification (38.3% vs. 20%, p < 0.01), bronchiectasis (7.5% vs. 1.5%, p < 0.05), bronchiarctia (6.4% vs. 0.8%, p < 0.05), and right upper lobe involvement (57.5% vs. 33.1%, p < 0.01), left upper lobe involvement (46.8% vs. 33.1%, p < 0.05) and lymphadenopathy (58.5% vs. 37.7%, p < 0.01). The study found that when pulmonary tuberculosis patients have consolidation, cavity, upper lobe involvement and lymphadenopathy on chest CT images, they may have a higher risk of AFB-positive tuberculosis.