Acceptability, feasibility, and impact of a pilot tuberculosis literacy and treatment counselling intervention: a mixed methods study

• Published in: BMC infectious diseases Vol. 21; no. 1; p. 449
• Main Authors: Law, Stephanie, Seepamore, Boitumelo, Oxlade, Olivia, Sikhakhane, Nondumiso, Dawood, Halima, Chetty, Sheldon, Padayatchi, Nesri, Menzies, Dick, Daftary, Amrita
• Format: Journal Article
• Language: English
• Published: England BioMed Central Ltd 18.05.2021; BioMed Central; BMC
• Subjects: Acceptability; Care and treatment; Counseling; Data collection; Diagnostic systems; Drug therapy; Education and counselling; Educational aspects; Empowerment; Feasibility studies; Health counseling; HIV; Human immunodeficiency virus; Intervention; Literacy; Methods; Mixed methods intervention; Mixed methods research; Patient education; Patients; Provider engagement; Regression models; Retention; Social work; South Africa; Students; Time series; Training; Tuberculosis; South Africa; South Africa; Education and counselling; Tuberculosis; Provider engagement; Mixed methods intervention
• ISSN: 1471-2334; 1471-2334
• DOI: 10.1186/s12879-021-06136-1

There is a need for innovative strategies to improve TB testing uptake and patient retention along the continuum of TB care early-on in treatment without burdening under-resourced health systems. We used a mixed methods approach to develop and pilot test a tuberculosis literacy and counselling intervention at an urban clinic in KwaZulu Natal, South Africa, to improve TB testing uptake and retention in tuberculosis care. We engaged in discussions with clinic staff to plan and develop the intervention, which was delivered by senior social work students who received one-week training. The intervention included: 1) group health talks with all patients attending the primary clinic; and 2) individual counselling sessions, using motivational interviewing techniques, with newly diagnosed tuberculosis patients. We compared social work students' tuberculosis knowledge, attitudes, and practices before and after their training. We assessed the change in number of tuberculosis diagnostic tests performed after implementation via an interrupted time series analysis with a quasi-Poisson regression model. We compared pre- and post-intervention probabilities of treatment initiation and completion using regression analyses, adjusting for potential baseline confounders. We conducted focus groups with the students, as well as brief surveys and one-on-one interviews with patients, to assess acceptability, feasibility, and implementation. During the study period, 1226 individuals received tuberculosis diagnostic testing and 163 patients started tuberculosis treatment, of whom 84 (51.5%) received individual counselling. The number of diagnostic tuberculosis tests performed increased by 1.36 (95%CI 1.23-1.58) times post-intervention, adjusting for background calendar trend. Probabilities of TB treatment initiation and treatment completion increased by 10.1% (95%CI 1.5-21.3%) and 4.4% (95%CI -7.3-16.0%), respectively. Patients found the counselling sessions alleviated anxiety and increased treatment self-efficacy. Social work students felt the clinic staff were collaborative and highly supportive of the intervention, and that it improved patient engagement and adherence. Engaging clinic staff in the development of an intervention ensures buy-in and collaboration. Education and counselling before and early-on in tuberculosis treatment can increase tuberculosis testing and treatment uptake. Training junior social workers can enable task-shifting in under-resourced settings, while addressing important service gaps in tuberculosis care.