Gō model revisited

This review discusses Gō models broadly used in biomolecular simulations. I start with a brief description of the original lattice model study by Nobuhiro Gō. Then, the theory of protein folding behind Gō model, free energy approaches, and off-lattice Gō models are reviewed. I also mention a stringe...

Full description

Saved in:
Bibliographic Details
Published inBiophysics and Physicobiology Vol. 16; pp. 248 - 255
Main Author Takada, Shoji
Format Journal Article
LanguageEnglish
Published Japan The Biophysical Society of Japan 01.01.2019
The Biophysical Society of Japan (BSJ)
Subjects
coarse-grained simulation
funnel energy landscape
Gō model
protein folding
Review
structure-based model
structure-based model
coarse-grained simulation
Gō model
protein folding
funnel energy landscape
Online AccessGet full text

Cover

More Information
Summary:This review discusses Gō models broadly used in biomolecular simulations. I start with a brief description of the original lattice model study by Nobuhiro Gō. Then, the theory of protein folding behind Gō model, free energy approaches, and off-lattice Gō models are reviewed. I also mention a stringent test for the assumption in Gō models given from all-atom molecular dynamics simulations. Subsequently, I move to application of Gō models to protein dynamical functions. Various extension of Gō models is also reviewed. Finally, some publicly available tools to use Gō models are listed.
Bibliography:ObjectType-Article-2
SourceType-Scholarly Journals-1
ObjectType-Feature-3
content type line 23
ObjectType-Review-1
ISSN:2189-4779
2189-4779
DOI:10.2142/biophysico.16.0_248