Recent development of nanoparticles for molecular imaging

Molecular imaging enables us to non-invasively visualize cellular functions and biological processes in living subjects, allowing accurate diagnosis of diseases at early stages. For successful molecular imaging, a suitable contrast agent with high sensitivity is required. To date, various nanopartic...

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Published inPhilosophical transactions of the Royal Society of London. Series A: Mathematical, physical, and engineering sciences Vol. 375; no. 2107; p. 20170022
Main Authors Kim, Jonghoon, Lee, Nohyun, Hyeon, Taeghwan
Format Journal Article
LanguageEnglish
Published England The Royal Society Publishing 28.11.2017
Subjects
Biological activity
Contrast Agent
Contrast agents
Crystallization
Kidney stones
Medical imaging
Molecular Imaging
Molecular structure
Nanomaterials
Nanoparticle
Nanoparticles
Opinion Piece
Physical properties
molecular imaging
nanoparticle
contrast agent
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ISSN1364-503X
1471-2962
1471-2962
DOI10.1098/rsta.2017.0022

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Summary:Molecular imaging enables us to non-invasively visualize cellular functions and biological processes in living subjects, allowing accurate diagnosis of diseases at early stages. For successful molecular imaging, a suitable contrast agent with high sensitivity is required. To date, various nanoparticles have been developed as contrast agents for medical imaging modalities. In comparison with conventional probes, nanoparticles offer several advantages, including controllable physical properties, facile surface modification and long circulation time. In addition, they can be integrated with various combinations for multimodal imaging and therapy. In this opinion piece, we highlight recent advances and future perspectives of nanomaterials for molecular imaging. This article is part of the themed issue ‘Challenges for chemistry in molecular imaging’.
Bibliography:Discussion meeting issue 'Challenges for chemistry in molecular imaging' organised and edited by David Parker, Nicholas J Long and Stephen Faulkner
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One contribution of 10 to a discussion meeting issue ‘Challenges for chemistry in molecular imaging’.
ISSN:1364-503X
1471-2962
1471-2962
DOI:10.1098/rsta.2017.0022