Clinicoanatomical correlation in stroke related aphasia

• Published in: Annals of the Indian Academy of Neurology Vol. 18; no. 4; pp. 424 - 429
• Main Authors: Bohra, Vikram, Khwaja, Geeta Anjum, Jain, Sneh, Duggal, Ashish, Ghuge, Vijay Vishwanath, Srivastava, Abhilekh
• Format: Journal Article
• Language: English
• Published: India Medknow Publications and Media Pvt. Ltd 01.10.2015; Medknow Publications & Media Pvt. Ltd; Medknow Publications & Media Pvt Ltd; Wolters Kluwer Medknow Publications
• Subjects: Aphasia; Cardiomyopathy; Cardiovascular disease; Care and treatment; clinico-anatomic correlation; clinico-topographic correlation; Coronary vessels; Diabetes; Localization; Medical imaging; NMR; Nuclear magnetic resonance; Original; Stroke; Studies; India; Aphasia; clinico-topographic correlation; stroke; clinico-anatomic correlation
• ISSN: 0972-2327; 1998-3549
• DOI: 10.4103/0972-2327.165469

With advances in neuroimaging, traditional views regarding the clinicoanatomic correlation in stroke patients with aphasia are being challenged and it has been observed that lesions at a given cortical or subcortical site may manifest with different aphasia profiles. To study as to whether there is a strict clinicoanatomical correlation between the type of aphasia and lesion site in patients with first ever stroke. Observational study, based in a tertiary care center. Stroke patient's ≥18 years of age were screened and those with first ever stroke and aphasia were subjected to a detailed stroke workup and language assessment using the Hindi version of Western Aphasia Battery (WAB). Statistical analysis was done with χ(2) test with Yates correction and Kruskal-Wallis test. The level of significance was set at P < 0.05. Overall aphasia was detected in 27.9% of the 260 screened cases with stroke. Amongst 60 cases with first ever stroke and aphasia, the aphasia type was: Global (33.33%), Broca's (28.3%), transcortical motor (13.33%), transcortical sensory (10%), Wernicke's (8.33%), anomic (5%), and conduction (1.67%) aphasia. A definite correlation between the lesion site and the type of aphasia as per the traditional classification was observed in 35% cases only. No absolute correlation exists between the lesion site and the type of clinical aphasia syndrome in majority of the patients with cortical and subcortical stroke.