Spread of a SARS-CoV-2 variant through Europe in the summer of 2020

Following its emergence in late 2019, the spread of SARS-CoV-2 1 , 2 has been tracked by phylogenetic analysis of viral genome sequences in unprecedented detail 3 – 5 . Although the virus spread globally in early 2020 before borders closed, intercontinental travel has since been greatly reduced. How...

Full description

Saved in:
Bibliographic Details
Published inNature (London) Vol. 595; no. 7869; pp. 707 - 712
Main Authors Hodcroft, Emma B., Zuber, Moira, Nadeau, Sarah, Vaughan, Timothy G., Crawford, Katharine H. D., Althaus, Christian L., Reichmuth, Martina L., Bowen, John E., Walls, Alexandra C., Corti, Davide, Bloom, Jesse D., Veesler, David, Mateo, David, Hernando, Alberto, Comas, Iñaki, González-Candelas, Fernando, Stadler, Tanja, Neher, Richard A.
Format Journal Article
LanguageEnglish
Published London Nature Publishing Group UK 29.07.2021
Nature Publishing Group
Subjects
Online AccessGet full text

Cover

Loading…
More Information
Summary:Following its emergence in late 2019, the spread of SARS-CoV-2 1 , 2 has been tracked by phylogenetic analysis of viral genome sequences in unprecedented detail 3 – 5 . Although the virus spread globally in early 2020 before borders closed, intercontinental travel has since been greatly reduced. However, travel within Europe resumed in the summer of 2020. Here we report on a SARS-CoV-2 variant, 20E (EU1), that was identified in Spain in early summer 2020 and subsequently spread across Europe. We find no evidence that this variant has increased transmissibility, but instead demonstrate how rising incidence in Spain, resumption of travel, and lack of effective screening and containment may explain the variant’s success. Despite travel restrictions, we estimate that 20E (EU1) was introduced hundreds of times to European countries by summertime travellers, which is likely to have undermined local efforts to minimize infection with SARS-CoV-2. Our results illustrate how a variant can rapidly become dominant even in the absence of a substantial transmission advantage in favourable epidemiological settings. Genomic surveillance is critical for understanding how travel can affect transmission of SARS-CoV-2, and thus for informing future containment strategies as travel resumes. Analysis of the spread of the 20E (EU1) variant of SARS-CoV-2 through Europe suggests that international travel and insufficient containment, rather than increased transmissibility, led to a resurgence of infections.
Bibliography:ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 23
ISSN:0028-0836
1476-4687
DOI:10.1038/s41586-021-03677-y