The mediator role of resilience between psychological predictors and health-related quality of life in breast cancer survivors: a cross-sectional study

• Published in: BMC cancer Vol. 22; no. 1; p. 57
• Main Authors: Zhou, Kaina, Ning, Fan, Wang, Wen, Li, Xiaomei
• Format: Journal Article
• Language: English
• Published: England BioMed Central Ltd 12.01.2022; BioMed Central; BMC
• Subjects: Adult; Analysis; Breast cancer; Breast Neoplasms - psychology; Cancer survivors; Cancer Survivors - psychology; Cancer Survivors - statistics & numerical data; Cancer therapies; Care and treatment; Comorbidity; Coping (Psychology); Coping style; Cross-Sectional Studies; Female; Health aspects; Health-related quality of life; Humans; Middle Aged; Patient outcomes; Perceived social support; Perceptions; Quality of life; Quality of Life - psychology; Questionnaires; Regression analysis; Resilience; Resilience (Personality trait); Resilience, Psychological - physiology; Risk factors; Sample size; Social aspects; Social interactions; Social networks; Social Support; Sociodemographics; Tumors; China; Health-related quality of life; Breast cancer; Coping style; Perceived social support; Resilience
• ISSN: 1471-2407; 1471-2407
• DOI: 10.1186/s12885-022-09177-0

Although many psychological factors have been associated with health-related quality of life (HRQoL), the mediator role of resilience between psychological predictors (i.e., coping styles and perceived social support) and HRQoL has rarely been explored in breast cancer survivors (BCSs). A total of 231 BCSs participated in this cross-sectional survey. Pearson correlation was performed to analyze the relationships among coping styles (confrontation, avoidance, and resignation), perceived social support, resilience, and HRQoL. A multivariate linear regression analysis was applied to identify the psychological predictors of HRQoL and resilience, respectively. A structural equation modeling (SEM) was employed to examine the mediating role of resilience between coping styles, perceived social support, and HRQoL. Perceived social support and resilience were positively associated with confrontation. Resilience was positively associated with perceived social support. HRQoL had positive correlations with confrontation/avoidance, perceived social support, and resilience. Resilience and resignation/avoidance were significant independent predictors of HRQoL, while resignation/confrontation and perceived social support were significant independent predictors of resilience. Confrontation/resignation, perceived social support, and resilience had significant direct effects on HRQoL; confrontation/resignation and perceived social support had significant direct effects on resilience; resilience had significant mediator roles between confrontation/resignation, perceived social support, and HRQoL. Resilience was a significant mediator between coping styles, perceived social support, and HRQoL. A resilience-oriented intervention is recommended to alleviate the detrimental influences of low resilience on HRQoL, providing a new strategy for improving the health status of BCSs.