肝移植术后宫腔内人工授精成功妊娠并足月分娩一例及文献复习

肝移植是终末期肝脏疾病患者的最终选择。大部分生育年龄的女性患者接受肝移植后能很快恢复正常生活,并希望养育后代。通过自然受孕并顺利分娩的患者并不少见,但仍有部分患者因为各种原因出现不孕。关于不孕的器官移植后患者接受辅助生殖技术（assisted reproductive technology,ART）实现妊娠的报道极少,因为这不仅涉及到复杂的伦理问题,而且需要多个学科间的联合协作。ART的目的必须以健康妊娠为前提,最大限度地降低母体和胎儿并发症。本文介绍了1例不孕的肝移植术后患者,经过宫腔内人工授精（intrauterine insemination,IUI）成功妊娠并足月分娩,探讨妊娠对移植肝...

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Published in国际妇产科学杂志 Vol. 43; no. 4; pp. 403 - 406
Main Author 林凯璇 周秋明 李鸿儒 吴元赭
Format Journal Article
LanguageChinese
Published 210002,南京军区南京总医院妇产科%210002,南京军区南京总医院生殖医学中心 2016
Subjects
伦理学,医学
妊娠
授精,人工
生殖技术,辅助
肝移植
Pregnancy
伦理学,医学
Insemination,artificial
授精,人工
生殖技术,辅助
Reproductive technology,assisted
妊娠
肝移植
Liver transplantation
Ethics,medical
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Summary:肝移植是终末期肝脏疾病患者的最终选择。大部分生育年龄的女性患者接受肝移植后能很快恢复正常生活,并希望养育后代。通过自然受孕并顺利分娩的患者并不少见,但仍有部分患者因为各种原因出现不孕。关于不孕的器官移植后患者接受辅助生殖技术（assisted reproductive technology,ART）实现妊娠的报道极少,因为这不仅涉及到复杂的伦理问题,而且需要多个学科间的联合协作。ART的目的必须以健康妊娠为前提,最大限度地降低母体和胎儿并发症。本文介绍了1例不孕的肝移植术后患者,经过宫腔内人工授精（intrauterine insemination,IUI）成功妊娠并足月分娩,探讨妊娠对移植肝脏的影响及免疫抑制剂和肝移植对妊娠的影响。
Bibliography:12-1399/R
Liver transplantation is the final choice of the end-stage liver disease. Most of childbearing age women regainto normal life, hoping to bring up offspring. Although quite a few of these patients get conception and delivery without a hitch,still portion of them are infertile because of all kinds of reasons. Cases about infertile patients who had accepted assistedreproductive technology （ART） after organ transplantation are rare, since these not only refer to complicated ethical nature, butalso require multi -disciplines collaboration. ART premises healthy pregnancy as well as minimizes maternal and fetalcomplications. This review introduced a case that a liver transplant patient who succeeded to be pregnant following intrauterineinsemination and delivered at full-time, and also discusses the influences among graft, pregnancy and immunosuppressor.
LIN Kai-xuan, ZHOU Qiu-ming,LI Hong-ru,WU Yuan-zhe. （Department of Obstetrics and Gynecology Center of Reproductive MedicineNanjing General Hospital of Nanji
ISSN:1674-1870