Overview of the coagulation system
Coagulation is a dynamic process and the understanding of the blood coagulation system has evolved over the recent years in anaesthetic practice. Although the traditional classification of the coagulation system into extrinsic and intrinsic pathway is still valid, the newer insights into coagulation...
Saved in:
| Published in | Indian journal of anaesthesia Vol. 58; no. 5; pp. 515 - 523 |
|---|---|
| Main Authors | , , |
| Format | Journal Article |
| Language | English |
| Published |
India
Medknow Publications and Media Pvt. Ltd
01.09.2014
Medknow Publications & Media Pvt. Ltd Medknow Publications & Media Pvt Ltd Wolters Kluwer Medknow Publications |
| Subjects | |
| Online Access | Get full text |
| ISSN | 0019-5049 0976-2817 |
| DOI | 10.4103/0019-5049.144643 |
Cover
Loading…
| Abstract | Coagulation is a dynamic process and the understanding of the blood coagulation system has evolved over the recent years in anaesthetic practice. Although the traditional classification of the coagulation system into extrinsic and intrinsic pathway is still valid, the newer insights into coagulation provide more authentic description of the same. Normal coagulation pathway represents a balance between the pro coagulant pathway that is responsible for clot formation and the mechanisms that inhibit the same beyond the injury site. Imbalance of the coagulation system may occur in the perioperative period or during critical illness, which may be secondary to numerous factors leading to a tendency of either thrombosis or bleeding. A systematic search of literature on PubMed with MeSH terms 'coagulation system, haemostasis and anaesthesia revealed twenty eight related clinical trials and review articles in last 10 years. Since the balance of the coagulation system may tilt towards bleeding and thrombosis in many situations, it is mandatory for the clinicians to understand physiologic basis of haemostasis in order to diagnose and manage the abnormalities of the coagulation process and to interpret the diagnostic tests done for the same. |
|---|---|
| AbstractList | Coagulation is a dynamic process and the understanding of the blood coagulation system has evolved over the recent years in anaesthetic practice. Although the traditional classification of the coagulation system into extrinsic and intrinsic pathway is still valid, the newer insights into coagulation provide more authentic description of the same. Normal coagulation pathway represents a balance between the pro coagulant pathway that is responsible for clot formation and the mechanisms that inhibit the same beyond the injury site. Imbalance of the coagulation system may occur in the perioperative period or during critical illness, which may be secondary to numerous factors leading to a tendency of either thrombosis or bleeding. A systematic search of literature on PubMed with MeSH terms 'coagulation system, haemostasis and anaesthesia revealed twenty eight related clinical trials and review articles in last 10 years. Since the balance of the coagulation system may tilt towards bleeding and thrombosis in many situations, it is mandatory for the clinicians to understand physiologic basis of haemostasis in order to diagnose and manage the abnormalities of the coagulation process and to interpret the diagnostic tests done for the same.Coagulation is a dynamic process and the understanding of the blood coagulation system has evolved over the recent years in anaesthetic practice. Although the traditional classification of the coagulation system into extrinsic and intrinsic pathway is still valid, the newer insights into coagulation provide more authentic description of the same. Normal coagulation pathway represents a balance between the pro coagulant pathway that is responsible for clot formation and the mechanisms that inhibit the same beyond the injury site. Imbalance of the coagulation system may occur in the perioperative period or during critical illness, which may be secondary to numerous factors leading to a tendency of either thrombosis or bleeding. A systematic search of literature on PubMed with MeSH terms 'coagulation system, haemostasis and anaesthesia revealed twenty eight related clinical trials and review articles in last 10 years. Since the balance of the coagulation system may tilt towards bleeding and thrombosis in many situations, it is mandatory for the clinicians to understand physiologic basis of haemostasis in order to diagnose and manage the abnormalities of the coagulation process and to interpret the diagnostic tests done for the same. Coagulation is a dynamic process and the understanding of the blood coagulation system has evolved over the recent years in anaesthetic practice. Although the traditional classification of the coagulation system into extrinsic and intrinsic pathway is still valid, the newer insights into coagulation provide more authentic description of the same. Normal coagulation pathway represents a balance between the pro coagulant pathway that is responsible for clot formation and the mechanisms that inhibit the same beyond the injury site. Imbalance of the coagulation system may occur in the perioperative period or during critical illness, which may be secondary to numerous factors leading to a tendency of either thrombosis or bleeding. A systematic search of literature on PubMed with MeSH terms ′coagulation system, haemostasis and anaesthesia revealed twenty eight related clinical trials and review articles in last 10 years. Since the balance of the coagulation system may tilt towards bleeding and thrombosis in many situations, it is mandatory for the clinicians to understand physiologic basis of haemostasis in order to diagnose and manage the abnormalities of the coagulation process and to interpret the diagnostic tests done for the same. |
| Audience | Academic |
| Author | Palta, Sanjeev Palta, Anshu Saroa, Richa |
| AuthorAffiliation | 1 Department of Pathology, Government Medical College and Hospital, Chandigarh, India Department of Anaesthesiology and Intensive Care, Government Medical College and Hospital, Chandigarh, India |
| AuthorAffiliation_xml | – name: Department of Anaesthesiology and Intensive Care, Government Medical College and Hospital, Chandigarh, India – name: 1 Department of Pathology, Government Medical College and Hospital, Chandigarh, India |
| Author_xml | – sequence: 1 givenname: Sanjeev surname: Palta fullname: Palta, Sanjeev – sequence: 2 givenname: Richa surname: Saroa fullname: Saroa, Richa – sequence: 3 givenname: Anshu surname: Palta fullname: Palta, Anshu |
| BackLink | https://www.ncbi.nlm.nih.gov/pubmed/25535411$$D View this record in MEDLINE/PubMed |
| BookMark | eNp1kktr3DAUhUVJaR7tvqsytBC68VRvW5tACE0bCGTTroUsXXk02FZq2VPy7ytnMm0mTNFCQvrOkXTvOUVHfewBofcELznB7AvGRBUCc7UknEvOXqETrEpZ0IqUR3m9Oz5GpymtMWaUSfkGHVMhmOCEnKCPdxsYNgF-L6JfjCtY2GiaqTVjiP0iPaQRurfotTdtgndP8xn6ef31x9X34vbu283V5W1hJZVj4QyDElcgiVRecOtLyhklQAyhnhnuSM1rK0sFyllhK1dVmFPqqHCCqtqwM3Sz9XXRrPX9EDozPOhogn7ciEOjzTAG24LGBnj24KUXFSd1WdUKO1lhTytcqtJnr4ut1_1Ud-As9ONg2j3T_ZM-rHQTN5pTiakS2eDzk8EQf02QRt2FZKFtTQ9xSppIjhnDlNCMfnqBruM09LlUmaJC5aJj8Y9qTP5A6H3M99rZVF8yRVnuGCGZKg5QDfSQH5l770Pe3uOXB_g8HHTBHhScPxOswLTjKsV2mvud9sEPzyv4t3S76GRAbgE7xJQG8NqG8TE3-Qmh1QTrOaN6DqGeQ6i3Gc1C_EK48_6v5A_23uHS |
| CitedBy_id | crossref_primary_10_3389_fpls_2019_00261 crossref_primary_10_1016_j_isci_2024_109788 crossref_primary_10_3390_biom11071027 crossref_primary_10_1016_j_jep_2022_115511 crossref_primary_10_3390_molecules23112859 crossref_primary_10_1016_j_jns_2019_01_027 crossref_primary_10_21518_2307_1109_2021_11_1_58_66 crossref_primary_10_2174_1389203724666230908114115 crossref_primary_10_1007_s11239_020_02326_x crossref_primary_10_2174_18753183_v13_230714_2023_1 crossref_primary_10_58920_sciphar02030055 crossref_primary_10_1055_a_2223_2369 crossref_primary_10_1128_iai_00476_23 crossref_primary_10_1097_MBC_0000000000001296 crossref_primary_10_1542_neo_23_2_e82 crossref_primary_10_3390_ijms24097732 crossref_primary_10_1053_j_jvca_2019_06_016 crossref_primary_10_15171_ijbsm_2019_17 crossref_primary_10_3389_fimmu_2024_1392000 crossref_primary_10_1016_j_bcdf_2023_100399 crossref_primary_10_1021_acsbiomaterials_4c01658 crossref_primary_10_1021_acschembio_0c00439 crossref_primary_10_1021_acs_orglett_2c02320 crossref_primary_10_1186_s12959_021_00303_9 crossref_primary_10_1007_s00068_024_02468_0 crossref_primary_10_1111_iwj_14527 crossref_primary_10_3389_fbioe_2020_00100 crossref_primary_10_1016_j_media_2025_103475 crossref_primary_10_1039_D2SC01108E crossref_primary_10_1002_adfm_201909011 crossref_primary_10_3390_math12152422 crossref_primary_10_1007_s11239_023_02776_z crossref_primary_10_2217_rme_2022_0035 crossref_primary_10_1021_acs_jproteome_4c00995 crossref_primary_10_1016_j_toxicon_2020_07_020 crossref_primary_10_1007_s00705_022_05575_8 crossref_primary_10_3390_biomedicines8100441 crossref_primary_10_3390_ijms241612563 crossref_primary_10_1007_s12672_022_00610_1 crossref_primary_10_3390_nu15010187 crossref_primary_10_22141_2224_0586_20_5_2024_1741 crossref_primary_10_1111_febs_15149 crossref_primary_10_1371_journal_pone_0153006 crossref_primary_10_1007_s12033_019_00187_1 crossref_primary_10_3390_nu16030432 crossref_primary_10_1371_journal_pone_0222240 crossref_primary_10_3390_ijms23010574 crossref_primary_10_1177_0271678X20921974 crossref_primary_10_1111_jth_14685 crossref_primary_10_1080_09537104_2018_1508649 crossref_primary_10_3389_fphys_2020_596057 crossref_primary_10_15360_1813_9779_2024_5_24_30 crossref_primary_10_1016_j_pharma_2024_08_005 crossref_primary_10_1213_ANE_0000000000006756 crossref_primary_10_1016_j_thromres_2022_04_018 crossref_primary_10_3390_ijms22052762 crossref_primary_10_1055_s_0043_57011 crossref_primary_10_3390_polysaccharides2010006 crossref_primary_10_3390_jnt4030018 crossref_primary_10_3390_medicina59091614 crossref_primary_10_1088_1361_6560_ab25a6 crossref_primary_10_36290_vnl_2024_015 crossref_primary_10_1093_jalm_jfaa060 crossref_primary_10_1055_a_2195_3927 crossref_primary_10_7759_cureus_40023 crossref_primary_10_1093_biohorizons_hzw015 crossref_primary_10_1039_D2MO00171C crossref_primary_10_15407_ubj93_02_062 crossref_primary_10_1080_15563650_2025_2451642 crossref_primary_10_3390_ijms20246335 crossref_primary_10_5937_jomb0_35847 crossref_primary_10_3390_biomedicines9070776 crossref_primary_10_4049_jimmunol_1900503 crossref_primary_10_1002_iub_2777 crossref_primary_10_3389_frph_2021_794352 crossref_primary_10_1080_17460441_2024_2368743 crossref_primary_10_12968_bjon_2022_31_21_1096 crossref_primary_10_3390_ijms23042064 crossref_primary_10_3892_etm_2023_12359 crossref_primary_10_3390_ijms221810140 crossref_primary_10_7759_cureus_73112 crossref_primary_10_1038_s41598_025_87117_1 crossref_primary_10_3389_fpubh_2023_1309094 crossref_primary_10_1016_j_blre_2020_100731 crossref_primary_10_1016_j_bpa_2022_10_002 crossref_primary_10_1007_s11897_024_00671_z crossref_primary_10_1177_08971900241247628 crossref_primary_10_3389_fimmu_2021_778913 crossref_primary_10_1177_20503121211002996 crossref_primary_10_1111_ger_12327 crossref_primary_10_3390_biomedicines11102781 crossref_primary_10_1097_TA_0000000000003902 crossref_primary_10_3389_fbioe_2021_807679 crossref_primary_10_1038_s10038_022_01071_8 crossref_primary_10_1007_s40719_020_00183_w crossref_primary_10_3390_cells12050678 crossref_primary_10_33086_ijmlst_v4i2_2683 crossref_primary_10_4037_aacnacc2019771 crossref_primary_10_4103_joah_joah_47_19 crossref_primary_10_1111_joim_20008 crossref_primary_10_1016_j_mehy_2019_02_037 crossref_primary_10_1007_s12011_021_03036_y crossref_primary_10_3390_md22030139 crossref_primary_10_1016_j_mehy_2022_110898 crossref_primary_10_1161_ATVBAHA_123_319255 crossref_primary_10_1038_s41440_020_0515_0 crossref_primary_10_3390_ijms231810436 crossref_primary_10_1016_j_actpha_2021_02_013 crossref_primary_10_18231_j_jpbs_2022_004 crossref_primary_10_1016_j_rpth_2024_102581 crossref_primary_10_1002_jcp_26065 crossref_primary_10_1016_j_ejmhg_2018_01_003 crossref_primary_10_3390_ijms221910803 crossref_primary_10_1152_ajpgi_00402_2017 crossref_primary_10_3390_cells11060939 crossref_primary_10_1016_j_jiec_2024_08_035 crossref_primary_10_1007_s10930_023_10116_6 crossref_primary_10_3389_fphar_2023_1180262 crossref_primary_10_3390_biomedicines9121950 crossref_primary_10_1038_s41598_024_64093_6 crossref_primary_10_1111_jfbc_13094 crossref_primary_10_3389_fcell_2024_1372355 crossref_primary_10_1177_1076029620954282 crossref_primary_10_1098_rsif_2021_0023 crossref_primary_10_1016_j_pmatsci_2022_100997 crossref_primary_10_1016_j_mpaic_2015_11_004 crossref_primary_10_36384_01232576_336 crossref_primary_10_3390_jcm9113461 crossref_primary_10_1080_10255842_2022_2124858 crossref_primary_10_51847_NwP6JzwyQu crossref_primary_10_1016_j_tiv_2019_03_031 crossref_primary_10_34198_ejcs_3120_7791 crossref_primary_10_1002_smll_202401144 crossref_primary_10_3390_ijms26031393 crossref_primary_10_20408_jti_2021_0052 crossref_primary_10_1093_ptj_pzac057 crossref_primary_10_1016_j_amjcard_2024_03_003 crossref_primary_10_1016_j_tru_2022_100110 crossref_primary_10_1016_j_amj_2024_05_007 crossref_primary_10_1016_j_compbiolchem_2024_108246 crossref_primary_10_1007_s11182_019_01803_y crossref_primary_10_1177_1076029620959724 crossref_primary_10_3390_toxins15020158 crossref_primary_10_1021_acs_jmedchem_2c00845 crossref_primary_10_1093_jn_nxaa153 crossref_primary_10_1016_j_jcis_2025_02_207 crossref_primary_10_1016_j_rpth_2023_102160 crossref_primary_10_1002_ddr_21407 crossref_primary_10_1016_j_tcam_2021_100532 crossref_primary_10_1080_09537104_2024_2337907 crossref_primary_10_1134_S1990750823600358 crossref_primary_10_1016_j_colsurfb_2024_113927 crossref_primary_10_3390_polym11111906 crossref_primary_10_1007_s10989_018_9682_0 crossref_primary_10_1055_a_2056_1561 crossref_primary_10_3389_fnins_2021_675732 crossref_primary_10_1007_s12032_023_02207_2 crossref_primary_10_1039_D0BM00781A crossref_primary_10_3389_fimmu_2024_1395479 crossref_primary_10_3390_antiox10030387 crossref_primary_10_1016_j_aspen_2017_03_023 crossref_primary_10_1051_ject_201850237 crossref_primary_10_1186_s40001_023_01328_8 crossref_primary_10_15407_ubj90_02_014 crossref_primary_10_2217_rme_2020_0082 crossref_primary_10_3390_cells13040305 crossref_primary_10_3390_md18100514 crossref_primary_10_1016_j_foodres_2024_114324 crossref_primary_10_1186_s13287_023_03582_3 crossref_primary_10_3390_ijms25168727 crossref_primary_10_1002_prp2_70014 crossref_primary_10_3389_fphys_2022_885183 crossref_primary_10_1177_2324709618800349 crossref_primary_10_1590_1519_6984_219186 crossref_primary_10_3390_toxins12060358 crossref_primary_10_3390_biom9110649 crossref_primary_10_1111_1744_9987_13567 crossref_primary_10_1007_s12274_022_5226_1 crossref_primary_10_1038_s41401_022_00892_9 crossref_primary_10_1248_bpb_b24_00291 crossref_primary_10_3390_ijms22062834 crossref_primary_10_1002_clc_70008 crossref_primary_10_3390_cells10113140 crossref_primary_10_1136_rapm_2024_105674 crossref_primary_10_1016_j_tracli_2023_03_007 crossref_primary_10_1152_physrev_00035_2020 crossref_primary_10_1126_scisignal_aan2787 crossref_primary_10_1128_JVI_01853_17 crossref_primary_10_1371_journal_pone_0178943 crossref_primary_10_1016_j_tiv_2019_04_010 crossref_primary_10_1161_ATVBAHA_122_318439 crossref_primary_10_1177_03000605231152384 crossref_primary_10_1186_s40729_021_00314_1 crossref_primary_10_3390_ph14121301 crossref_primary_10_1007_s10571_019_00767_4 crossref_primary_10_15275_rusomj_2021_0210 crossref_primary_10_1136_openhrt_2021_001785 crossref_primary_10_1021_acsami_0c13098 crossref_primary_10_1080_00207454_2020_1732372 crossref_primary_10_3390_bioengineering6030069 crossref_primary_10_1021_acsnano_4c00833 crossref_primary_10_3389_fphys_2022_796837 crossref_primary_10_3390_hemato1020009 crossref_primary_10_12968_jpar_2018_10_3_118 crossref_primary_10_3390_diseases10040073 crossref_primary_10_1016_j_biopha_2016_09_057 crossref_primary_10_1016_j_heliyon_2024_e28047 crossref_primary_10_1007_s10439_017_1817_5 crossref_primary_10_1016_j_fsi_2018_03_041 crossref_primary_10_17116_kardio202114041292 crossref_primary_10_1016_j_ihj_2025_02_007 crossref_primary_10_1016_j_plefa_2021_102268 crossref_primary_10_3389_fmicb_2022_846884 crossref_primary_10_11124_JBISRIR_2017_003470 crossref_primary_10_1177_1358863X231206778 crossref_primary_10_1097_TA_0000000000002521 crossref_primary_10_2174_0115734129282400240417115747 crossref_primary_10_1007_s00335_018_9761_8 crossref_primary_10_3390_md20100654 crossref_primary_10_1002_advs_202501857 crossref_primary_10_1039_D1TB02523F crossref_primary_10_17749_2313_7347_ob_gyn_rep_2021_214 crossref_primary_10_1186_s12882_017_0457_1 crossref_primary_10_33086_ijmlst_v5i2_3791 crossref_primary_10_3389_fcvm_2023_1269011 crossref_primary_10_2106_JBJS_RVW_20_00001 crossref_primary_10_4103_ija_IJA_1259_20 crossref_primary_10_1080_21505594_2018_1526531 crossref_primary_10_3389_fviro_2023_1327745 crossref_primary_10_1016_j_neuint_2024_105823 crossref_primary_10_1016_j_toxlet_2020_05_014 crossref_primary_10_1111_iwj_14048 crossref_primary_10_7759_cureus_41805 crossref_primary_10_1016_j_mtchem_2023_101465 crossref_primary_10_12968_jowc_2022_31_5_380 crossref_primary_10_1016_j_cobme_2017_12_001 crossref_primary_10_3390_ijms241411856 crossref_primary_10_1016_j_neuro_2019_02_020 crossref_primary_10_1002_lt_26352 crossref_primary_10_3389_fnins_2020_00762 crossref_primary_10_1007_s11255_017_1729_1 crossref_primary_10_1111_ijlh_13349 crossref_primary_10_1016_j_bbcan_2023_189053 crossref_primary_10_4236_jbise_2022_157017 crossref_primary_10_1002_ptr_7368 crossref_primary_10_1016_j_jvn_2021_07_006 crossref_primary_10_1016_j_matdes_2020_108913 crossref_primary_10_1055_s_0043_1774796 crossref_primary_10_1016_j_isci_2024_110723 crossref_primary_10_1016_j_jtha_2022_09_001 crossref_primary_10_3390_biomedicines9080867 crossref_primary_10_1016_j_ijbiomac_2023_127951 crossref_primary_10_1016_j_carbpol_2024_122782 crossref_primary_10_1177_20458940211022204 crossref_primary_10_1016_j_anclin_2018_07_006 crossref_primary_10_1016_j_mpsur_2024_02_011 crossref_primary_10_1182_bloodadvances_2022007444 crossref_primary_10_3103_S0096392523010042 crossref_primary_10_1515_tjb_2020_0357 crossref_primary_10_1039_D3TB01900D crossref_primary_10_1016_j_omton_2024_200909 crossref_primary_10_1167_tvst_10_14_7 crossref_primary_10_1021_acsanm_3c01805 crossref_primary_10_1021_acsomega_3c00215 crossref_primary_10_1161_CIRCGEN_117_001956 crossref_primary_10_3390_biology11050683 crossref_primary_10_3390_cancers11081103 crossref_primary_10_1016_j_thromres_2020_07_027 crossref_primary_10_1039_D4LC00216D crossref_primary_10_2174_1381612825666191216125135 crossref_primary_10_1111_vox_12875 crossref_primary_10_1002_cbdv_201800558 crossref_primary_10_1007_s11239_021_02440_4 crossref_primary_10_1155_2017_5690625 crossref_primary_10_1097_SLA_0000000000005882 crossref_primary_10_34133_2022_9780569 crossref_primary_10_1007_s00210_024_03380_5 crossref_primary_10_1021_acs_molpharmaceut_4c01156 crossref_primary_10_1126_scitranslmed_aay4860 crossref_primary_10_1007_s13238_022_00915_5 crossref_primary_10_1186_s12959_023_00479_2 crossref_primary_10_1002_jbm_a_36763 crossref_primary_10_1038_s41380_021_01197_9 crossref_primary_10_1186_s13567_024_01407_6 crossref_primary_10_1016_j_jpra_2022_06_004 crossref_primary_10_1111_jth_14374 crossref_primary_10_1016_j_jep_2023_116562 crossref_primary_10_1096_fj_202001146RR crossref_primary_10_1155_2020_4359305 crossref_primary_10_1080_17460441_2016_1188077 crossref_primary_10_1016_j_bioorg_2019_03_004 crossref_primary_10_3390_biomedicines12081880 crossref_primary_10_2903_j_efsa_2024_8953 crossref_primary_10_1371_journal_pone_0174771 crossref_primary_10_23736_S2724_5276_23_07214_2 crossref_primary_10_1021_acs_jmedchem_5c00048 crossref_primary_10_1088_2516_1091_ac23a4 crossref_primary_10_1016_j_thromres_2020_05_034 crossref_primary_10_1155_2022_2918654 crossref_primary_10_1002_jpen_2644 crossref_primary_10_58427_apghn_3_2_2024_1_7 crossref_primary_10_1089_adt_2020_1010 crossref_primary_10_20473_ijar_V2I22020_59_66 crossref_primary_10_1126_sciadv_abj6901 crossref_primary_10_1097_TA_0000000000003027 crossref_primary_10_1080_87559129_2021_1934002 crossref_primary_10_1212_WNL_0000000000209616 crossref_primary_10_17721_1728_2748_2018_76_42_46 crossref_primary_10_1016_j_thromres_2022_08_016 crossref_primary_10_1055_a_2235_7485 crossref_primary_10_1016_j_bios_2022_114615 crossref_primary_10_3390_bios13080817 crossref_primary_10_17721_2616_6410_2016_21_53_57 crossref_primary_10_1016_j_conctc_2020_100535 crossref_primary_10_1186_s12890_021_01784_0 crossref_primary_10_4014_jmb_2207_07037 crossref_primary_10_1177_1708538120915997 crossref_primary_10_1039_D4TB00074A crossref_primary_10_1177_10225536241233473 crossref_primary_10_1002_jbm_a_36985 crossref_primary_10_1016_j_actbio_2020_09_036 crossref_primary_10_1055_a_1839_0355 crossref_primary_10_3390_pharmaceutics13081153 crossref_primary_10_1016_j_toxicon_2017_03_015 crossref_primary_10_1016_j_memsci_2024_122669 crossref_primary_10_1038_s41598_019_39080_x crossref_primary_10_1002_pat_5559 crossref_primary_10_1093_biomethods_bpz006 crossref_primary_10_1007_s00210_024_03453_5 crossref_primary_10_3390_ijms24021744 crossref_primary_10_1188_19_CJON_431_433 crossref_primary_10_5005_newborn_3_1_iv crossref_primary_10_3390_gels9060477 crossref_primary_10_3390_jcm10153349 crossref_primary_10_1002_jex2_34 crossref_primary_10_1002_rth2_12815 crossref_primary_10_1007_s00419_023_02496_z crossref_primary_10_3389_fbioe_2021_716184 crossref_primary_10_3390_ijms22115980 crossref_primary_10_1016_j_nano_2017_11_007 crossref_primary_10_3389_fphys_2023_1094249 crossref_primary_10_1136_bmjmed_2022_000239 crossref_primary_10_3390_biomedicines12020274 crossref_primary_10_3390_ijms22115746 crossref_primary_10_1007_s12539_018_0310_7 crossref_primary_10_1016_j_lfs_2021_119120 crossref_primary_10_1080_07388551_2022_2036691 crossref_primary_10_3390_ijms23116022 crossref_primary_10_1039_D1BM01351C crossref_primary_10_3389_fbioe_2018_00004 crossref_primary_10_1016_j_biocel_2024_106616 crossref_primary_10_1089_ten_tea_2020_0011 crossref_primary_10_1097_CRD_0000000000000227 crossref_primary_10_1007_s10853_024_09595_4 crossref_primary_10_1021_acsmaterialsau_3c00021 crossref_primary_10_3390_ijms24076243 crossref_primary_10_1016_j_lfs_2021_120021 crossref_primary_10_1111_1759_7714_15121 crossref_primary_10_4049_jimmunol_2101033 crossref_primary_10_3390_ijms25105228 crossref_primary_10_3389_fimmu_2024_1368852 crossref_primary_10_2147_RRTM_S244912 crossref_primary_10_1016_j_btre_2019_e00330 crossref_primary_10_1016_j_ttbdis_2018_11_005 crossref_primary_10_1021_acsami_1c24557 crossref_primary_10_18273_revmed_v33n2_2020008 crossref_primary_10_1007_s11356_017_9782_y crossref_primary_10_1007_s40719_023_00258_4 crossref_primary_10_1007_s11845_024_03617_5 crossref_primary_10_2309_JAVA_D_22_00006 crossref_primary_10_12968_hmed_2021_0111 crossref_primary_10_1016_j_ijbiomac_2024_139191 crossref_primary_10_1016_j_toxlet_2020_08_009 crossref_primary_10_1055_a_2330_1371 crossref_primary_10_1007_s10928_021_09783_8 crossref_primary_10_1007_s12012_025_09971_9 crossref_primary_10_1016_j_thromres_2023_10_001 crossref_primary_10_3389_fgene_2022_957655 crossref_primary_10_1038_s41415_023_6010_7 crossref_primary_10_33084_bjop_v3i3_1394 crossref_primary_10_1002_adhm_202202984 crossref_primary_10_15252_msb_20188793 crossref_primary_10_20965_jrm_2020_p0362 crossref_primary_10_2174_2772574X14666230522114039 crossref_primary_10_1016_j_jconrel_2018_02_020 crossref_primary_10_1097_SHK_0000000000002009 crossref_primary_10_1093_jas_skac124 crossref_primary_10_3390_coatings11111394 crossref_primary_10_1111_nyas_13454 crossref_primary_10_1208_s12248_024_00966_y crossref_primary_10_1007_s12975_024_01295_0 crossref_primary_10_1080_09537104_2021_1981849 crossref_primary_10_1089_met_2021_0022 crossref_primary_10_1038_cmi_2016_1 crossref_primary_10_3389_fmars_2023_1327408 crossref_primary_10_1007_s11906_023_01258_0 crossref_primary_10_1016_j_jtha_2024_02_007 crossref_primary_10_1249_JSR_0000000000000682 crossref_primary_10_3390_ani12030361 crossref_primary_10_1016_j_toxicon_2023_107572 crossref_primary_10_1002_adhm_202200574 crossref_primary_10_1111_jfbc_13407 crossref_primary_10_1097_SHK_0000000000002238 crossref_primary_10_1007_s11182_021_02280_y crossref_primary_10_1016_j_intimp_2025_114218 crossref_primary_10_3389_fvets_2024_1369515 crossref_primary_10_1016_j_dwt_2024_100217 crossref_primary_10_1042_CS20180155 crossref_primary_10_1016_j_watres_2024_122037 crossref_primary_10_25122_jml_2021_0316 crossref_primary_10_1016_j_molliq_2018_04_071 crossref_primary_10_1016_j_mtadv_2020_100117 crossref_primary_10_1097_SHK_0000000000001389 crossref_primary_10_1016_j_compbiolchem_2019_107116 crossref_primary_10_3233_JAD_220720 crossref_primary_10_3390_ijms242015328 crossref_primary_10_1021_acs_nanolett_2c02019 crossref_primary_10_1016_j_ab_2020_113708 crossref_primary_10_1016_j_ejmhg_2017_10_004 crossref_primary_10_3390_cells8101160 crossref_primary_10_1016_j_ijbiomac_2019_12_216 crossref_primary_10_3390_ijms252413634 crossref_primary_10_3389_fimmu_2017_00846 crossref_primary_10_3390_molecules27134054 crossref_primary_10_1016_j_jcot_2020_07_003 crossref_primary_10_1039_D3NR02593D crossref_primary_10_3390_ijms22020897 crossref_primary_10_1016_j_carbpol_2018_12_056 crossref_primary_10_1038_s12276_024_01375_z crossref_primary_10_1007_s12291_021_00972_3 crossref_primary_10_25284_2519_2078_1_106__2024_300623 crossref_primary_10_1098_rsob_210318 crossref_primary_10_23736_S0392_9590_22_04861_1 crossref_primary_10_1186_s13024_024_00754_4 crossref_primary_10_18311_jnr_2024_35928 crossref_primary_10_3390_ijms23158283 crossref_primary_10_1002_prp2_698 crossref_primary_10_3389_fchem_2019_00280 crossref_primary_10_3390_jcm12134265 crossref_primary_10_1038_s41422_019_0260_6 crossref_primary_10_3390_cells12091222 crossref_primary_10_1080_17474086_2021_1860002 crossref_primary_10_1007_s00289_022_04300_4 crossref_primary_10_1002_advs_201900133 crossref_primary_10_1177_00405175241280538 crossref_primary_10_1042_BST20210600 crossref_primary_10_1016_j_bpj_2024_11_018 crossref_primary_10_3390_ijms25010218 crossref_primary_10_1016_j_bios_2020_112167 crossref_primary_10_1051_mbcb_2022025 crossref_primary_10_1080_17435390_2024_2323070 crossref_primary_10_15360_1813_9779_2019_5_74_87 crossref_primary_10_1097_MJT_0000000000000985 crossref_primary_10_1039_D2SC04962G crossref_primary_10_3389_fcvm_2021_632131 crossref_primary_10_1016_j_cell_2021_01_004 crossref_primary_10_1021_acs_jproteome_0c00425 crossref_primary_10_1039_D3BM01338C crossref_primary_10_1021_acsabm_9b00544 crossref_primary_10_3390_life12010077 crossref_primary_10_1115_1_4050647 crossref_primary_10_1021_acs_biomac_8b01704 crossref_primary_10_1016_j_jaad_2021_03_108 crossref_primary_10_3389_fimmu_2021_626200 crossref_primary_10_1080_17476348_2022_2119131 crossref_primary_10_17721_2616_6410_2017_22_58_61 crossref_primary_10_1016_j_rpth_2025_102708 crossref_primary_10_1016_j_injury_2024_111386 crossref_primary_10_3389_fmed_2018_00253 crossref_primary_10_3906_vet_1811_29 crossref_primary_10_1007_s13346_020_00751_2 crossref_primary_10_1016_j_molliq_2018_06_032 crossref_primary_10_1016_j_ab_2019_03_004 crossref_primary_10_1016_j_ijbiomac_2023_128574 crossref_primary_10_1097_MBC_0000000000001355 crossref_primary_10_3390_cells12182278 crossref_primary_10_3390_ijms22137113 crossref_primary_10_1002_rth2_12534 crossref_primary_10_3390_jcm10010140 crossref_primary_10_1016_j_tifs_2021_12_012 crossref_primary_10_3390_v9030042 crossref_primary_10_1016_j_plabm_2020_e00193 crossref_primary_10_1111_joic_12529 crossref_primary_10_1038_s41598_024_60170_y crossref_primary_10_4037_aacnacc2019867 crossref_primary_10_3390_cells13110991 crossref_primary_10_1002_jbm_b_34806 crossref_primary_10_1093_rb_rbac063 crossref_primary_10_6000_1929_5995_2024_13_16 crossref_primary_10_3389_fcvm_2025_1541879 crossref_primary_10_1002_EXP_20240229 crossref_primary_10_1177_08971900221132680 crossref_primary_10_1016_j_ijbiomac_2025_141742 crossref_primary_10_2478_aspr_2023_0018 crossref_primary_10_1016_j_heliyon_2023_e16254 crossref_primary_10_1007_s40089_021_00340_2 crossref_primary_10_1016_j_cbd_2024_101265 crossref_primary_10_1364_BOE_500434 crossref_primary_10_1111_xen_12680 crossref_primary_10_55959_MSU0137_0952_16_78_1_6 crossref_primary_10_1016_j_biomaterials_2023_122097 crossref_primary_10_1016_j_transproceed_2020_10_005 crossref_primary_10_3389_fonc_2023_1099857 crossref_primary_10_1016_j_jstrokecerebrovasdis_2021_106163 crossref_primary_10_1021_acs_molpharmaceut_2c00626 crossref_primary_10_1186_s13018_024_04748_2 crossref_primary_10_1080_09205063_2024_2384275 crossref_primary_10_3390_mi10070429 crossref_primary_10_1177_25424823251327674 crossref_primary_10_1016_j_chemolab_2024_105197 crossref_primary_10_1016_j_heliyon_2024_e38203 crossref_primary_10_1002_jcla_23129 crossref_primary_10_1016_j_neunet_2024_106732 crossref_primary_10_3390_ijms24032519 crossref_primary_10_1016_j_ejmech_2016_05_039 crossref_primary_10_1016_j_jpeds_2020_01_051 crossref_primary_10_1016_j_talanta_2020_121241 crossref_primary_10_1161_JAHA_123_030525 crossref_primary_10_1371_journal_pone_0192965 crossref_primary_10_1016_j_ijbiomac_2024_130771 crossref_primary_10_1016_j_nantod_2024_102216 crossref_primary_10_1016_j_biopha_2023_115421 crossref_primary_10_3390_v12121351 crossref_primary_10_1007_s12035_021_02457_z crossref_primary_10_3390_ijms20081811 crossref_primary_10_14710_ik_ijms_26_2_110_116 crossref_primary_10_3390_ijms22031218 crossref_primary_10_1080_14786419_2023_2169919 crossref_primary_10_1016_j_jddst_2024_105612 crossref_primary_10_3390_ebj5020009 crossref_primary_10_1007_s11696_025_03890_3 crossref_primary_10_1212_WNL_0000000000011931 crossref_primary_10_1002_adbi_202101108 crossref_primary_10_1007_s00586_024_08306_6 crossref_primary_10_1038_s41598_020_60934_2 crossref_primary_10_1016_j_trsl_2017_06_002 crossref_primary_10_1111_ans_15912 crossref_primary_10_1016_j_resplu_2023_100477 crossref_primary_10_3390_jcm11164932 crossref_primary_10_3390_ijms241813870 crossref_primary_10_1021_acsami_9b22277 crossref_primary_10_1007_s13760_020_01456_6 crossref_primary_10_1177_08853282231189931 crossref_primary_10_1152_ajplung_00434_2020 crossref_primary_10_1021_acs_bioconjchem_2c00492 crossref_primary_10_3389_fbioe_2023_1272348 crossref_primary_10_2174_1874070701812010095 crossref_primary_10_1007_s13671_018_0234_9 crossref_primary_10_1016_j_actbio_2018_11_029 crossref_primary_10_3390_cancers16132356 crossref_primary_10_1016_j_fbio_2024_105467 crossref_primary_10_1002_mgg3_1166 crossref_primary_10_3390_bioengineering9120765 crossref_primary_10_1002_iid3_769 crossref_primary_10_7759_cureus_67758 crossref_primary_10_1002_adhm_202001094 crossref_primary_10_1097_MAT_0000000000002048 crossref_primary_10_1016_j_biomaterials_2021_121301 crossref_primary_10_1016_j_jaut_2019_102347 crossref_primary_10_1016_j_rpth_2024_102614 crossref_primary_10_1016_j_toxicon_2016_02_005 crossref_primary_10_1055_s_0042_1756305 crossref_primary_10_1016_j_forsciint_2023_111689 crossref_primary_10_1002_pbc_28934 |
| Cites_doi | 10.1097/00000441-200410000-00002 10.1161/CIRCULATIONAHA.110.936773 10.1111/j.1365-2141.2007.06548.x 10.1016/S0889-8588(18)30503-3 10.1111/j.1741-6892.2004.00428.x 10.1097/01.CCM.0000126360.00450.F8 10.1186/cc11278 10.1182/asheducation-2013.1.464 10.1016/S0741-5214(03)01033-4 10.1080/08880010290097233 10.1093/bja/85.3.446 10.1093/qjmed/hcg129 10.1093/bjaceaccp/mks061 10.1111/j.1538-7836.2007.02776.x 10.1093/bja/aeh174 10.1007/s12262-011-0407-2 10.1186/cc12527 10.1111/j.1365-2141.2005.05444.x 10.1097/CCM.0b013e3181c9cbd9 10.1016/j.thromres.2004.07.020 10.1146/annurev.biochem.67.1.395 10.1111/j.1365-2044.2004.03679.x 10.1097/00003246-200205001-00024 10.1016/j.critrevonc.2006.06.004 10.1016/S0959-440X(98)80100-0 10.1093/clinchem/46.8.1260 10.1016/S0049-3848(96)00233-2 10.1007/BF03022247 10.1111/j.1538-7836.2008.02859.x 10.1046/j.1365-2141.2001.02892.x 10.1146/annurev-physiol-042210-121137 10.1160/TH09-11-0771 10.1016/j.bpobgyn.2009.11.010 10.1161/ATVBAHA.107.141911 |
| ContentType | Journal Article |
| Copyright | COPYRIGHT 2014 Medknow Publications and Media Pvt. Ltd. Copyright Medknow Publications & Media Pvt Ltd Sep-Oct 2014 Copyright: © Indian Journal of Anaesthesia 2014 |
| Copyright_xml | – notice: COPYRIGHT 2014 Medknow Publications and Media Pvt. Ltd. – notice: Copyright Medknow Publications & Media Pvt Ltd Sep-Oct 2014 – notice: Copyright: © Indian Journal of Anaesthesia 2014 |
| DBID | AAYXX CITATION NPM 3V. 7X7 7XB 8FI 8FJ 8FK 8G5 ABUWG AFKRA AZQEC BENPR CCPQU DWQXO FYUFA GHDGH GNUQQ GUQSH K9. M0S M2O MBDVC PHGZM PHGZT PIMPY PKEHL PQEST PQQKQ PQUKI PRINS Q9U 7X8 5PM DOA |
| DOI | 10.4103/0019-5049.144643 |
| DatabaseName | CrossRef PubMed ProQuest Central (Corporate) Health & Medical Collection ProQuest Central (purchase pre-March 2016) Hospital Premium Collection Hospital Premium Collection (Alumni Edition) ProQuest Central (Alumni) (purchase pre-March 2016) ProQuest Research Library ProQuest Central (Alumni) ProQuest Central UK/Ireland ProQuest Central Essentials - QC ProQuest Central Database Suite (ProQuest) ProQuest One ProQuest Central Proquest Health Research Premium Collection Health Research Premium Collection (Alumni) ProQuest Central Student ProQuest Research Library ProQuest Health & Medical Complete (Alumni) ProQuest Health & Medical Collection Research Library Research Library (Corporate) ProQuest Central Premium ProQuest One Academic (New) Publicly Available Content Database ProQuest One Academic Middle East (New) ProQuest One Academic Eastern Edition (DO NOT USE) ProQuest One Academic ProQuest One Academic UKI Edition ProQuest Central China ProQuest Central Basic MEDLINE - Academic PubMed Central (Full Participant titles) Directory of Open Access Journals |
| DatabaseTitle | CrossRef PubMed Publicly Available Content Database Research Library Prep ProQuest Central Student ProQuest One Academic Middle East (New) ProQuest Central Essentials ProQuest Health & Medical Complete (Alumni) ProQuest Central (Alumni Edition) ProQuest One Community College Research Library (Alumni Edition) ProQuest Central China ProQuest Central Health Research Premium Collection Health and Medicine Complete (Alumni Edition) ProQuest Central Korea ProQuest Research Library ProQuest Central (New) ProQuest Central Basic ProQuest One Academic Eastern Edition ProQuest Hospital Collection Health Research Premium Collection (Alumni) ProQuest Hospital Collection (Alumni) ProQuest Health & Medical Complete ProQuest One Academic UKI Edition ProQuest One Academic ProQuest One Academic (New) ProQuest Central (Alumni) MEDLINE - Academic |
| DatabaseTitleList | MEDLINE - Academic Publicly Available Content Database PubMed |
| Database_xml | – sequence: 1 dbid: DOA name: DOAJ Directory of Open Access Journals url: https://www.doaj.org/ sourceTypes: Open Website – sequence: 2 dbid: NPM name: PubMed url: https://proxy.k.utb.cz/login?url=http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed sourceTypes: Index Database – sequence: 3 dbid: BENPR name: ProQuest Central url: https://www.proquest.com/central sourceTypes: Aggregation Database |
| DeliveryMethod | fulltext_linktorsrc |
| EISSN | 0976-2817 |
| EndPage | 523 |
| ExternalDocumentID | oai_doaj_org_article_0ae4c5c47f5841b78b90d680f280797f PMC4260295 3500320431 A392381711 25535411 10_4103_0019_5049_144643 |
| Genre | Journal Article Review |
| GeographicLocations | India |
| GeographicLocations_xml | – name: India |
| GroupedDBID | --- 2WC 53G 5VS 7X7 8FI 8FJ 8G5 AAYXX ABDBF ABUWG ACGFO ACGFS ACIHN ACUHS ADBBV ADJBI ADRAZ AEAQA AFKRA AHMBA ALIPV ALMA_UNASSIGNED_HOLDINGS AOIJS AZQEC BAWUL BCNDV BENPR BPHCQ BVXVI C1A CCPQU CITATION DIK DWQXO E3Z EBD EBS EJD EOJEC ESX F5P FYUFA GNUQQ GROUPED_DOAJ GUQSH GX1 H13 HMCUK HYE IAO IEA IHR IHW IL9 INH INR IOF IPNFZ ITC KQ8 M2O M48 O5R O5S OBODZ OK1 OVD P2P PGMZT PHGZM PHGZT PIMPY PQQKQ PROAC RIG RMW RNS RPM TEORI TR2 TUS UKHRP W3E XSB NPM PMFND 3V. 7XB 8FK K9. MBDVC PKEHL PQEST PQUKI PRINS Q9U 7X8 5PM PUEGO |
| ID | FETCH-LOGICAL-c626t-da3e708e6169f54cf724321e1a12f3a4d1b4bc679e9dc5c8d880422d25d529ba3 |
| IEDL.DBID | M48 |
| ISSN | 0019-5049 |
| IngestDate | Wed Aug 27 01:20:41 EDT 2025 Thu Aug 21 18:16:14 EDT 2025 Thu Jul 10 18:39:01 EDT 2025 Mon Jun 30 13:55:42 EDT 2025 Tue Jun 17 21:30:15 EDT 2025 Thu Jun 12 23:07:23 EDT 2025 Tue Jun 10 20:21:17 EDT 2025 Thu May 22 20:48:55 EDT 2025 Thu Apr 03 07:07:54 EDT 2025 Tue Jul 01 02:06:15 EDT 2025 Thu Apr 24 22:53:24 EDT 2025 |
| IsDoiOpenAccess | true |
| IsOpenAccess | true |
| IsPeerReviewed | true |
| IsScholarly | true |
| Issue | 5 |
| Keywords | Anaesthesia Coagulation system haemostasis |
| Language | English |
| License | This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
| LinkModel | DirectLink |
| MergedId | FETCHMERGED-LOGICAL-c626t-da3e708e6169f54cf724321e1a12f3a4d1b4bc679e9dc5c8d880422d25d529ba3 |
| Notes | ObjectType-Article-1 SourceType-Scholarly Journals-1 content type line 14 ObjectType-Feature-2 ObjectType-Review-3 content type line 23 |
| OpenAccessLink | https://doaj.org/article/0ae4c5c47f5841b78b90d680f280797f |
| PMID | 25535411 |
| PQID | 1625932305 |
| PQPubID | 226517 |
| PageCount | 9 |
| ParticipantIDs | doaj_primary_oai_doaj_org_article_0ae4c5c47f5841b78b90d680f280797f pubmedcentral_primary_oai_pubmedcentral_nih_gov_4260295 proquest_miscellaneous_1640330212 proquest_journals_1625932305 gale_infotracmisc_A392381711 gale_infotracgeneralonefile_A392381711 gale_infotracacademiconefile_A392381711 gale_healthsolutions_A392381711 pubmed_primary_25535411 crossref_citationtrail_10_4103_0019_5049_144643 crossref_primary_10_4103_0019_5049_144643 |
| ProviderPackageCode | CITATION AAYXX |
| PublicationCentury | 2000 |
| PublicationDate | 2014-09-01 |
| PublicationDateYYYYMMDD | 2014-09-01 |
| PublicationDate_xml | – month: 09 year: 2014 text: 2014-09-01 day: 01 |
| PublicationDecade | 2010 |
| PublicationPlace | India |
| PublicationPlace_xml | – name: India – name: Belagaum |
| PublicationTitle | Indian journal of anaesthesia |
| PublicationTitleAlternate | Indian J Anaesth |
| PublicationYear | 2014 |
| Publisher | Medknow Publications and Media Pvt. Ltd Medknow Publications & Media Pvt. Ltd Medknow Publications & Media Pvt Ltd Wolters Kluwer Medknow Publications |
| Publisher_xml | – name: Medknow Publications and Media Pvt. Ltd – name: Medknow Publications & Media Pvt. Ltd – name: Medknow Publications & Media Pvt Ltd – name: Wolters Kluwer Medknow Publications |
| References | Corral (key-10.4103/0019-5049.144643-29) 2007 Thornton (key-10.4103/0019-5049.144643-2) 2010 Cines (key-10.4103/0019-5049.144643-6) 1998 Coppola (key-10.4103/0019-5049.144643-37) 2003 Previtali (key-10.4103/0019-5049.144643-3) 2011 Bombeli (key-10.4103/0019-5049.144643-4) 2004 Triplett (key-10.4103/0019-5049.144643-8) 2000 Mackman (key-10.4103/0019-5049.144643-20) 2007 Achneck (key-10.4103/0019-5049.144643-1) 2010 Roberts (key-10.4103/0019-5049.144643-33) 2001 Schuster (key-10.4103/0019-5049.144643-42) 2007 Price (key-10.4103/0019-5049.144643-26) 2004 Ashby (key-10.4103/0019-5049.144643-11) 1990 Rigby (key-10.4103/0019-5049.144643-28) 2004 Pinjala (key-10.4103/0019-5049.144643-38) 2012 Franchini (key-10.4103/0019-5049.144643-36) 2006 Ejiofor (key-10.4103/0019-5049.144643-25) 2013 key-10.4103/0019-5049.144643-31 Myers (key-10.4103/0019-5049.144643-22) 2003 Polderman (key-10.4103/0019-5049.144643-34) 2012 key-10.4103/0019-5049.144643-14 key-10.4103/0019-5049.144643-15 key-10.4103/0019-5049.144643-17 Bauer (key-10.4103/0019-5049.144643-35) 2013 Jagneaux (key-10.4103/0019-5049.144643-40) 2004 Cesarman-Maus (key-10.4103/0019-5049.144643-41) 2005 Meybohm (key-10.4103/0019-5049.144643-5) 2013 Sadler (key-10.4103/0019-5049.144643-16) 1998 Lasne (key-10.4103/0019-5049.144643-7) 2006 Yenicesu (key-10.4103/0019-5049.144643-12) 2002 Owens (key-10.4103/0019-5049.144643-30) 2010 Manly (key-10.4103/0019-5049.144643-21) 2011 Opal (key-10.4103/0019-5049.144643-24) 2002 Colvin (key-10.4103/0019-5049.144643-13) 2004 Dahm (key-10.4103/0019-5049.144643-27) 2008 Closse (key-10.4103/0019-5049.144643-23) 1997 Doolittle (key-10.4103/0019-5049.144643-18) 1998 Kamath (key-10.4103/0019-5049.144643-19) 2003 Heemskerk (key-10.4103/0019-5049.144643-9) 2002 Martinelli (key-10.4103/0019-5049.144643-39) 2010 Andrews (key-10.4103/0019-5049.144643-10) 2004 Martlew (key-10.4103/0019-5049.144643-32) 2000 14603220 - J Vasc Surg. 2003 Nov;38(5):1075-89 9058490 - Thromb Res. 1997 Jan 15;85(2):159-64 20097136 - Best Pract Res Clin Obstet Gynaecol. 2010 Jun;24(3):339-52 15096242 - Anaesthesia. 2004 May;59(5):483-92 9572988 - Blood. 1998 May 15;91(10):3527-61 12004255 - Crit Care Med. 2002 May;30(5 Suppl):S325-31 11103188 - Br J Anaesth. 2000 Sep;85(3):446-55 15200603 - Vox Sang. 2004 Jul;87 Suppl1:43-6 2155902 - Hematol Oncol Clin North Am. 1990 Feb;4(1):1-26 15486534 - Am J Med Sci. 2004 Oct;328(4):196-204 23510484 - Crit Care. 2013 Mar 19;17(2):218 20083911 - Crit Care Med. 2010 Feb;38(2 Suppl):S3-9 23542761 - Indian J Surg. 2012 Apr;74(2):157-62 16766787 - Can J Anaesth. 2006 Jun;53(6 Suppl):S2-11 20539911 - Thromb Haemost. 2010 Sep;104(3):432-9 14500858 - QJM. 2003 Oct;96(10):711-29 12195687 - Thromb Haemost. 2002 Aug;88(2):186-93 16860994 - Crit Rev Oncol Hematol. 2006 Nov;60(2):144-51 17900274 - J Thromb Haemost. 2007 Dec;5(12):2315-22 9759493 - Annu Rev Biochem. 1998;67:395-424 18045239 - J Thromb Haemost. 2008 Feb;6(2):393-5 11529842 - Br J Haematol. 2001 Aug;114(2):249-57 15220183 - Br J Anaesth. 2004 Aug;93(2):275-87 15118541 - Crit Care Med. 2004 May;32(5 Suppl):S336-41 20690821 - Annu Rev Physiol. 2011;73:515-25 17556654 - Arterioscler Thromb Vasc Biol. 2007 Aug;27(8):1687-93 17391489 - Br J Haematol. 2007 Apr;137(2):99-108 12551825 - Haematologica. 2003 Jan;88(1):39-43 12186367 - Pediatr Hematol Oncol. 2002 Sep;19(6):433-7 9914253 - Curr Opin Struct Biol. 1998 Dec;8(6):792-8 10926920 - Clin Chem. 2000 Aug;46(8 Pt 2):1260-9 15507277 - Thromb Res. 2004;114(5-6):447-53 21084000 - Blood Transfus. 2011 Apr;9(2):120-38 21098468 - Circulation. 2010 Nov 16;122(20):2068-77 24319220 - Hematology Am Soc Hematol Educ Program. 2013;2013:464-70 15842654 - Br J Haematol. 2005 May;129(3):307-21 |
| References_xml | – start-page: 196 year: 2004 ident: key-10.4103/0019-5049.144643-40 article-title: Coagulation in sepsis publication-title: Am J Med Sci doi: 10.1097/00000441-200410000-00002 – start-page: 2068 year: 2010 ident: key-10.4103/0019-5049.144643-1 article-title: Pathophysiology of bleeding and clotting in the cardiac surgery patient: from vascular endothelium to circulatory assist device surface publication-title: Circulation doi: 10.1161/CIRCULATIONAHA.110.936773 – start-page: 99 year: 2007 ident: key-10.4103/0019-5049.144643-29 article-title: Protein Z/Z-dependent protease inhibitor (PZ/ZPI) anticoagulant system and thrombosis publication-title: Br J Haematol doi: 10.1111/j.1365-2141.2007.06548.x – start-page: 1 year: 1990 ident: key-10.4103/0019-5049.144643-11 article-title: Mechanisms of platelet activation and inhibition publication-title: Hematol Oncol Clin North Am doi: 10.1016/S0889-8588(18)30503-3 – start-page: 43 year: 2004 ident: key-10.4103/0019-5049.144643-13 article-title: Physiology of haemostasis publication-title: Vox Sang doi: 10.1111/j.1741-6892.2004.00428.x – start-page: S336 year: 2004 ident: key-10.4103/0019-5049.144643-28 article-title: Protein S: A conduit between anticoagulation and inflammation publication-title: Crit Care Med doi: 10.1097/01.CCM.0000126360.00450.F8 – start-page: A20 year: 2012 ident: key-10.4103/0019-5049.144643-34 article-title: Hypothermia and coagulation publication-title: Crit Care doi: 10.1186/cc11278 – start-page: 464 year: 2013 ident: key-10.4103/0019-5049.144643-35 article-title: Pros and cons of new oral anticoagulants publication-title: Hematology Am Soc Hematol Educ Program doi: 10.1182/asheducation-2013.1.464 – start-page: 1075 year: 2003 ident: key-10.4103/0019-5049.144643-22 article-title: P-selectin and leukocyte microparticles are associated with venous thrombogenesis publication-title: J Vasc Surg doi: 10.1016/S0741-5214(03)01033-4 – start-page: 39 year: 2003 ident: key-10.4103/0019-5049.144643-37 article-title: Von Willebrand factor in Italian centenarians publication-title: Haematologica – start-page: 433 year: 2002 ident: key-10.4103/0019-5049.144643-12 article-title: Virus-associated immune thrombocytopenic purpura in childhood publication-title: Pediatr Hematol Oncol doi: 10.1080/08880010290097233 – start-page: 446 year: 2000 ident: key-10.4103/0019-5049.144643-32 article-title: Peri-operative management of patients with coagulation disorders publication-title: Br J Anaesth doi: 10.1093/bja/85.3.446 – start-page: 711 year: 2003 ident: key-10.4103/0019-5049.144643-19 article-title: Fibrinogen: Biochemistry, epidemiology and determinants publication-title: QJM doi: 10.1093/qjmed/hcg129 – start-page: 87 year: 2013 ident: key-10.4103/0019-5049.144643-25 article-title: Anticlotting mechanisms I: Physiology and pathology publication-title: Contin Educ Anesth Crit Care Pain doi: 10.1093/bjaceaccp/mks061 – start-page: 2315 year: 2007 ident: key-10.4103/0019-5049.144643-42 article-title: Plasminogen deficiency publication-title: J Thromb Haemost doi: 10.1111/j.1538-7836.2007.02776.x – start-page: 275 year: 2004 ident: key-10.4103/0019-5049.144643-4 article-title: Updates in perioperative coagulation: Physiology and management of thromboembolism and haemorrhage publication-title: Br J Anaesth doi: 10.1093/bja/aeh174 – start-page: 157 year: 2012 ident: key-10.4103/0019-5049.144643-38 article-title: Thrombophilia - How far and how much to investigate? publication-title: Indian J Surg doi: 10.1007/s12262-011-0407-2 – start-page: 218 year: 2013 ident: key-10.4103/0019-5049.144643-5 article-title: Point-of-care coagulation management in intensive care medicine publication-title: Crit Care doi: 10.1186/cc12527 – start-page: 307 year: 2005 ident: key-10.4103/0019-5049.144643-41 article-title: Molecular mechanisms of fibrinolysis publication-title: Br J Haematol doi: 10.1111/j.1365-2141.2005.05444.x – start-page: S3 year: 2010 ident: key-10.4103/0019-5049.144643-39 article-title: Thrombotic risk factors: Basic pathophysiology publication-title: Crit Care Med doi: 10.1097/CCM.0b013e3181c9cbd9 – start-page: 3527 year: 1998 ident: key-10.4103/0019-5049.144643-6 article-title: Endothelial cells in physiology and in the pathophysiology of vascular disorders publication-title: Blood – start-page: 447 year: 2004 ident: key-10.4103/0019-5049.144643-10 article-title: Platelet physiology and thrombosis publication-title: Thromb Res doi: 10.1016/j.thromres.2004.07.020 – start-page: 395 year: 1998 ident: key-10.4103/0019-5049.144643-16 article-title: Biochemistry and genetics of von Willebrand factor publication-title: Annu Rev Biochem doi: 10.1146/annurev.biochem.67.1.395 – ident: key-10.4103/0019-5049.144643-31 – start-page: 483 year: 2004 ident: key-10.4103/0019-5049.144643-26 article-title: Tissue factor and tissue factor pathway inhibitor publication-title: Anaesthesia doi: 10.1111/j.1365-2044.2004.03679.x – start-page: S325 year: 2002 ident: key-10.4103/0019-5049.144643-24 article-title: Antithrombin, heparin, and heparan sulfate publication-title: Crit Care Med doi: 10.1097/00003246-200205001-00024 – start-page: 144 year: 2006 ident: key-10.4103/0019-5049.144643-36 article-title: Hemostasis and aging publication-title: Crit Rev Oncol Hematol doi: 10.1016/j.critrevonc.2006.06.004 – ident: key-10.4103/0019-5049.144643-14 – start-page: 792 year: 1998 ident: key-10.4103/0019-5049.144643-18 article-title: Three-dimensional structural studies on fragments of fibrinogen and fibrin publication-title: Curr Opin Struct Biol doi: 10.1016/S0959-440X(98)80100-0 – start-page: 1260 year: 2000 ident: key-10.4103/0019-5049.144643-8 article-title: Coagulation and bleeding disorders: Review and update publication-title: Clin Chem doi: 10.1093/clinchem/46.8.1260 – start-page: 159 year: 1997 ident: key-10.4103/0019-5049.144643-23 article-title: Influence of hypoxia and hypoxia-reoxygenation on endothelial P-selectin expression publication-title: Thromb Res doi: 10.1016/S0049-3848(96)00233-2 – ident: key-10.4103/0019-5049.144643-15 – ident: key-10.4103/0019-5049.144643-17 – start-page: 120 year: 2011 ident: key-10.4103/0019-5049.144643-3 article-title: Risk factors for venous and arterial thrombosis publication-title: Blood Transfus – start-page: S2 year: 2006 ident: key-10.4103/0019-5049.144643-7 article-title: From normal to pathological hemostasis publication-title: Can J Anesth doi: 10.1007/BF03022247 – start-page: 393 year: 2008 ident: key-10.4103/0019-5049.144643-27 article-title: The association between protein S levels and anticoagulant activity of tissue factor pathway inhibitor type 1 publication-title: J Thromb Haemost doi: 10.1111/j.1538-7836.2008.02859.x – start-page: 186 year: 2002 ident: key-10.4103/0019-5049.144643-9 article-title: Platelet activation and blood coagulation publication-title: Thromb Haemost – start-page: 249 year: 2001 ident: key-10.4103/0019-5049.144643-33 article-title: The dysfibrinogenaemias publication-title: Br J Haematol doi: 10.1046/j.1365-2141.2001.02892.x – start-page: 515 year: 2011 ident: key-10.4103/0019-5049.144643-21 article-title: Role of tissue factor in venous thrombosis publication-title: Annu Rev Physiol doi: 10.1146/annurev-physiol-042210-121137 – start-page: 432 year: 2010 ident: key-10.4103/0019-5049.144643-30 article-title: Tissue factor and thrombosis: The clot starts here publication-title: Thromb Haemost doi: 10.1160/TH09-11-0771 – start-page: 339 year: 2010 ident: key-10.4103/0019-5049.144643-2 article-title: Coagulation in pregnancy publication-title: Best Pract Res Clin Obstet Gynaecol doi: 10.1016/j.bpobgyn.2009.11.010 – start-page: 1687 year: 2007 ident: key-10.4103/0019-5049.144643-20 article-title: Role of the extrinsic pathway of blood coagulation in hemostasis and thrombosis publication-title: Arterioscler Thromb Vasc Biol doi: 10.1161/ATVBAHA.107.141911 – reference: 23510484 - Crit Care. 2013 Mar 19;17(2):218 – reference: 9914253 - Curr Opin Struct Biol. 1998 Dec;8(6):792-8 – reference: 18045239 - J Thromb Haemost. 2008 Feb;6(2):393-5 – reference: 20083911 - Crit Care Med. 2010 Feb;38(2 Suppl):S3-9 – reference: 9759493 - Annu Rev Biochem. 1998;67:395-424 – reference: 12186367 - Pediatr Hematol Oncol. 2002 Sep;19(6):433-7 – reference: 11529842 - Br J Haematol. 2001 Aug;114(2):249-57 – reference: 15220183 - Br J Anaesth. 2004 Aug;93(2):275-87 – reference: 20690821 - Annu Rev Physiol. 2011;73:515-25 – reference: 17391489 - Br J Haematol. 2007 Apr;137(2):99-108 – reference: 23542761 - Indian J Surg. 2012 Apr;74(2):157-62 – reference: 21098468 - Circulation. 2010 Nov 16;122(20):2068-77 – reference: 15507277 - Thromb Res. 2004;114(5-6):447-53 – reference: 15486534 - Am J Med Sci. 2004 Oct;328(4):196-204 – reference: 20539911 - Thromb Haemost. 2010 Sep;104(3):432-9 – reference: 15118541 - Crit Care Med. 2004 May;32(5 Suppl):S336-41 – reference: 15200603 - Vox Sang. 2004 Jul;87 Suppl1:43-6 – reference: 9058490 - Thromb Res. 1997 Jan 15;85(2):159-64 – reference: 10926920 - Clin Chem. 2000 Aug;46(8 Pt 2):1260-9 – reference: 11103188 - Br J Anaesth. 2000 Sep;85(3):446-55 – reference: 17900274 - J Thromb Haemost. 2007 Dec;5(12):2315-22 – reference: 21084000 - Blood Transfus. 2011 Apr;9(2):120-38 – reference: 20097136 - Best Pract Res Clin Obstet Gynaecol. 2010 Jun;24(3):339-52 – reference: 12004255 - Crit Care Med. 2002 May;30(5 Suppl):S325-31 – reference: 12551825 - Haematologica. 2003 Jan;88(1):39-43 – reference: 17556654 - Arterioscler Thromb Vasc Biol. 2007 Aug;27(8):1687-93 – reference: 16766787 - Can J Anaesth. 2006 Jun;53(6 Suppl):S2-11 – reference: 2155902 - Hematol Oncol Clin North Am. 1990 Feb;4(1):1-26 – reference: 9572988 - Blood. 1998 May 15;91(10):3527-61 – reference: 14603220 - J Vasc Surg. 2003 Nov;38(5):1075-89 – reference: 15096242 - Anaesthesia. 2004 May;59(5):483-92 – reference: 12195687 - Thromb Haemost. 2002 Aug;88(2):186-93 – reference: 24319220 - Hematology Am Soc Hematol Educ Program. 2013;2013:464-70 – reference: 14500858 - QJM. 2003 Oct;96(10):711-29 – reference: 16860994 - Crit Rev Oncol Hematol. 2006 Nov;60(2):144-51 – reference: 15842654 - Br J Haematol. 2005 May;129(3):307-21 |
| SSID | ssj0032366 |
| Score | 2.5199778 |
| SecondaryResourceType | review_article |
| Snippet | Coagulation is a dynamic process and the understanding of the blood coagulation system has evolved over the recent years in anaesthetic practice. Although the... |
| SourceID | doaj pubmedcentral proquest gale pubmed crossref |
| SourceType | Open Website Open Access Repository Aggregation Database Index Database Enrichment Source |
| StartPage | 515 |
| SubjectTerms | Anaesthesia Anesthesia Blood Blood clots Blood platelets Blood transfusions Coagulation Coagulation system Collagen Embolisms Endothelium haemostasis Hemophilia Hypoxia Medical research Medicine, Experimental Physiological aspects Physiology Proteins Review Surgery Thrombosis |
| SummonAdditionalLinks | – databaseName: Directory of Open Access Journals dbid: DOA link: http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwrV3PaxUxEA6lJy9FsepqtatIxcPyNr-TYyuW4kEvLfQWkmxSBdkn-qr_vjObfcsLSr14TSbL8mUmM0Mm3xDyWmWfZMi501azTkQTuxCi76yR4E2FzjJMbJ8f1cWV-HAtr3dafWFNWKEHLsCtep9ElBFXGUGDNsH2gzJ9RhoXqzOevuDztslUOYM54-WWEgKYTkIQXC4oBe35ahnDe00leOWQJt7-P0_nHfdUl07u-KLz--RgDiLb0_LzD8heGh-SV59-ot2nX-06txDWtXHtb-bmXG0hbD4kV-fvL99ddHMHhC5CorHpBs-T7k1SVNksRcyaCc5oop6yzL0YaBAhKm2THQAkM4A1CsYGJgfJbPD8Edkf12N6QlqVlUhWacpUFNwokzPk0ZbTwIMcgmnIaguDizM9OHap-OogTUDgsPrNOgTOFeAa8nZZ8a1QY9whe4bILnJIaj0NwFa7eavdv7a6Ice4L668EF1M051CjIdEg5Q25M0kgcYJPx_9_MYAIECaq0rypJK8KSTffxM8qgTB-mI9vVUSN1v_D0cxqQQd7GVDXi7TuBIr2sa0vkUZ0XOOBPsNeVx0akEH0jwuBX5cV9pWwVfPjF8-T9zg2HCAWfn0f-D9jNyD8FCUirojsr_5fpueQwi2CS8ma_sNzUInMg priority: 102 providerName: Directory of Open Access Journals – databaseName: Health & Medical Collection dbid: 7X7 link: http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwfV1Lb9QwELagXLggEK9AgYAQiIO18ds-oYKoKg5wodLerPi1IFVJabft38cTe0MjUK_xlyiZzNjfxJNvEHorUx-FSwkroyjmXnvsnO-x0SKvplwl4Sa1z2_y6Jh_XYt1_eB2Xssqd3PiNFGH0cM38hUBos4yYRYfT39j6BoFu6u1hcZtdAeky6CkS63nhCujy15lpjFYZCpctik56dhqPga7m5KzxbI0qff_O0dfW6SWBZTXVqTD--hepZLtQXn3D9CtODxEb75fQvTHq3ZMbSZ3rR_7TW3R1RbZ5kfo-PDLj89HuPZBwD6nG1scehZVp6Mk0iTBfVKUM0oi6QlNrOeBOO68VCaa4IXXIcckpzRQEQQ1rmeP0d4wDvEpamWSPBqpCJWeMy11SjmbNow45kRwukGrnRmsryLh0KvixOZkAQwHNXDGguFsMVyDPsxnnBaBjBuwn8CyMw6kracD49nG1kixXR95fgpwE82JU9qZLkjdJdDtMSo16BW8F1v-E50D1B5kpgdyg4Q06P2EgBDNN-_7-qdBNgGIXS2Q7xbITZH6_h9wfwHMMeiXwzsnsXUOOLd_PbZBr-dhOBPq2oY4XgCGd4yBzH6DnhSfmq2Tkz0mOFxcLbxtYb7lyPDr56QQDm0HqBHPbr6t5-hupn-8VMzto73t2UV8kSnW1r2c4ugPBeMfLw priority: 102 providerName: ProQuest |
| Title | Overview of the coagulation system |
| URI | https://www.ncbi.nlm.nih.gov/pubmed/25535411 https://www.proquest.com/docview/1625932305 https://www.proquest.com/docview/1640330212 https://pubmed.ncbi.nlm.nih.gov/PMC4260295 https://doaj.org/article/0ae4c5c47f5841b78b90d680f280797f |
| Volume | 58 |
| hasFullText | 1 |
| inHoldings | 1 |
| isFullTextHit | |
| isPrint | |
| link | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwfV1Lb9QwELZoe-GCQLwCZQkIgTikjd_2CbVoqwqJghAr9mbFjr1FqhJYtjz-PZ44CY1YuOxh_TnazH6TmYntbxB6JkLluQ2hkFqSgjnlCmtdVWjFYzRlMnDbqX2eidMFe7Pkyz_Ho3sDftta2kE_qcX64uDn11-vosPH_PWA4ZIeQppS8JjqwkpljLA7aC_GJQlu-paNawqU0LRyOaDTouXWK4BEMOeUM4wn8aqT9f_74X0lek13Vl4JVSc30Y0-x8yPEiluoWu-uY2evvsOjwX_I29DHrO-3LXVqu_dlSc95ztocTL_-Pq06BskFC7WIZuirqiXpfICCx04c0ESRgn2uMIk0IrV2DLrhNRe1447VUdnZYTUhNecaFvRu2i3aRt_H-UiCOa1kJgIx6gSKoRYZmuKLbW8tipDh4MZjOvVw6GJxYWJVQTYEDbHaQM2NMmGGXo5zviSlDP-gz0Gy4440LzuvmjXK9O7kCkrz-JdAH8Uw1Yqq8taqDKAoI-WIUOP4X8x6QDp6LnmKKaAoEOIcYZedAhgU_zxruqPIEQTgArWBPl8glwlDfBtwP0JMDqnmw4PJDEDtw2GmjPSseQZejIOw0zY8Nb49hIwrKQU9PczdC9xarTOQM0MyQnbJuabjjSfzzvpcOhHQDR_8M9rPkTXY0rI0i66fbS7WV_6RzHt2tgZ2pFLOUN7x_Oz9x9m3cuLWedh8fMTnf8G8Sgl6w |
| linkProvider | Scholars Portal |
| linkToHtml | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwtV1Lb9QwELbK9gAXBOIVKDQgHuIQbfxMfECohVZbWhaEWqm3NHbsBQklpd1S8af4jczESWgE6q3XeBI5k3l8jsffEPJc-dJJ432S6YwlwuY2McaWic4lZFOReWlats-5mh2ID4fycIX87s_CYFllHxPbQF01Fv-RTykCdQ6AWb49_pFg1yjcXe1baASz2HW_zmHJdvpm5z183xeMbW_tv5slXVeBxAJ4XyZVyV2W5k5Rpb0U1mdMcEYdLSnzvBQVNcJYlWmnKyttXoGFC8YqJivJtCk5PPcaWRUcljITsrq5Nf_8pY_9ML-wOwrAKZEAvsPGqKApnw7XcD9VCT5KhG2_gH-zwoW0OC7ZvJADt2-Rmx14jTeCtd0mK66-Q559-onxxp3HjY8BTsa2KRddU7A4EEXfJQdXoqN7ZFI3tXtAYuWVcFpllCkreK5y72H9rjk13MjK5BGZ9moobEdLjt0xvhewPEHFYdWdLlBxRVBcRF4PdxwHSo5LZDdRs4Mckmm3F5qTRdH5ZpGWTsBboGHmgposNzqtVJ56ZArSmY_IOn6XIpxMHUJCsQHYEgkOKY3Iq1YCgwJM3pbd2QZQAdJrjSRfjiQXgVz8f4JrI0Hwejse7o2k6KLOafHXRyLydBjGO7GSrnbNGcqIlHMk9o_I_WBTg3ZgecmlwIdnI2sbqW88Un_72nKSY6MDpuXDy6e1Tq7P9j_uFXs7891H5AaATxHq9dbIZHly5h4DwFuaJ51XxeToqh35DwbvXTQ |
| openUrl | ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=Overview+of+the+coagulation+system&rft.jtitle=Indian+journal+of+anaesthesia&rft.au=Palta%2C+Sanjeev&rft.au=Saroa%2C+Richa&rft.au=Palta%2C+Anshu&rft.date=2014-09-01&rft.issn=0019-5049&rft.volume=58&rft.issue=5&rft.spage=515&rft_id=info:doi/10.4103%2F0019-5049.144643&rft_id=info%3Apmid%2F25535411&rft.externalDocID=25535411 |
| thumbnail_l | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/lc.gif&issn=0019-5049&client=summon |
| thumbnail_m | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/mc.gif&issn=0019-5049&client=summon |
| thumbnail_s | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/sc.gif&issn=0019-5049&client=summon |