Photobiomodulation with Pulsed and Continuous Wave Near-Infrared Laser (810 nm, Al-Ga-As) Augments Dermal Wound Healing in Immunosuppressed Rats

• Published in: PloS one Vol. 11; no. 11; p. e0166705
• Main Authors: Keshri, Gaurav K., Gupta, Asheesh, Yadav, Anju, Sharma, Sanjeev K., Singh, Shashi Bala
• Format: Journal Article
• Language: English
• Published: United States Public Library of Science 18.11.2016; Public Library of Science (PLoS)
• Subjects: Actin; Adenosine Triphosphate - metabolism; Angiogenesis; Animals; Biological effects; Biology and Life Sciences; Biomarkers; Biopsy; Continuous radiation; Contraction; Cytochrome; Deoxyribonucleic acid; DNA; Engineering and Technology; Extracellular matrix; Fibroblast growth factor receptors; Fibronectin; Fibronectins; Gene therapy; Glucocorticoids; Healing; Heat shock proteins; Hydrocortisone; I.R. radiation; Immunocompromised Host; Inflammation; Infrared lasers; Injuries; Irradiation; Laser Therapy; Lasers; Light; Light therapy; Matrix Metalloproteinases - metabolism; Medicine and Health Sciences; Muscle proteins; NF-κB protein; Pain; Physiology; Pneumoviridae; Rats; Research and Analysis Methods; Restoration; Skin; Skin - pathology; Studies; Transforming growth factors; Tumor Necrosis Factor-alpha - metabolism; Tumor necrosis factor-α; Vascular endothelial growth factor; Vascularization; Wound care; Wound healing; Wound Healing - immunology; Wound Healing - radiation effects; India

Chronic non-healing cutaneous wounds are often vulnerable in one or more repair phases that prevent normal healing and pose challenges to the use of conventional wound care modalities. In immunosuppressed subject, the sequential stages of healing get hampered, which may be the consequences of dysreg...