CircRNA microarray profiling identifies a novel circulating biomarker for detection of gastric cancer

• Published in: Molecular cancer Vol. 17; no. 1; pp. 137 - 6
• Main Authors: Tang, Weiwei, Fu, Kai, Sun, Handong, Rong, Dawei, Wang, Hanjin, Cao, Hongyong
• Format: Journal Article
• Language: English
• Published: England BioMed Central Ltd 20.09.2018; BioMed Central; BMC
• Subjects: Biomarker; Biomarkers; Biosynthesis; Cancer patients; circRNAs; Data processing; Diagnosis; Disease; Exosomes; Gastric cancer; Gene expression; Genetic aspects; Health aspects; Letter to the Editor; Metastases; Microarray; Multivariate analysis; Plasma; RNA; Statistical analysis; Stomach cancer; Volcanoes; United States > US; China; Plasma; circRNAs; Biomarker; Exosomes; Microarray

CircRNA expression profiles for gastric cancer (GC) were screened using plasma samples from 10 GC patients with different TNM stages and 5 healthy individuals as controls. Results showed lower expression of circ-KIAA1244 in GC tissues, plasmas, and cells compare to normal controls. Further clinical...