Retinal detachment with spontaneous dialysis of the ora serrata in a 13-year-old child with neurofibromatosis type 1: A case report

• Published in: Indian journal of ophthalmology Vol. 68; no. 7; pp. 1473 - 1475
• Main Authors: Clemente-Tomás, Rodrigo, Ruíz-del Río, Noemí, Gargallo-Benedicto, Amparo, García-Ibor, Francisca, Hervas-Hernándis, José, Duch-Samper, Antonio
• Format: Journal Article
• Language: English
• Published: India Wolters Kluwer India Pvt. Ltd 01.07.2020; Medknow Publications and Media Pvt. Ltd; Medknow Publications & Media Pvt. Ltd; Wolters Kluwer - Medknow; Wolters Kluwer Medknow Publications
• Subjects: Adolescent; Brain cancer; Care and treatment; Case Reports; Case studies; Child; Ciliary Body; Collagen; Complications and side effects; Diagnosis; Dialysis; dialysis of the ora serrata; Fibroblasts; Genetic disorders; Hemodialysis; Humans; Neurofibromatosis; Neurofibromatosis 1 - complications; Neurofibromatosis 1 - diagnosis; neurofibromatosis type 1; Neurological disorders; Patient outcomes; Patients; Pediatric ophthalmology; Recklinghausen's disease; Renal Dialysis; Retina; Retina - diagnostic imaging; Retinal detachment; Retinal Detachment - diagnosis; Retinal Detachment - etiology; rhegmatogenous retinal detachment; Trauma; Tumors; vitreous base; India; neurofibromatosis type 1; vitreous base; Dialysis of the ora serrata; fibroblasts; rhegmatogenous retinal detachment
• ISSN: 0301-4738; 1998-3689
• DOI: 10.4103/ijo.IJO_1895_19

A 13-year-old child diagnosed with neurofibromatosis type 1 who on a routine control presented with rhegmatogenous retinal detachment associated to dialysis of the ora serrata in the left eye (OS). There were no clinical signs or history of contuse ocular trauma. Neurofibromatosis produces alterations in fibroblasts of the cortex of the vitreous base. This results in deficient production of the collagen fibers that anchor the vitreous base to the pars plana and the peripheral neurosensory retina. Thus, suboptimal function of the fibroblasts explains spontaneous avulsion of the vitreous base. Such avulsion in turn is related to dialysis of the ora serrata.