The association of syringe type and syringe cleaning with HCV infection among IDUs in Budapest, Hungary

• Published in: Drug and alcohol dependence Vol. 100; no. 3; pp. 240 - 247
• Main Authors: Gyarmathy, V. Anna, Neaigus, Alan, Mitchell, Mary M, Ujhelyi, Eszter
• Format: Journal Article
• Language: English
• Published: Shannon Elsevier Ireland Ltd 01.03.2009; Elsevier
• Subjects: Addictive behaviors; Adolescent; Adult; Adult and adolescent clinical studies; Biological and medical sciences; Central Europe; Cleaning; Drug addiction; Female; HCV infection; Hepatitis C; Hepatitis C - epidemiology; Hepatitis C - etiology; Hepatitis C - virology; Hepatitis C virus; Human viral diseases; Humans; Hungary - epidemiology; Infection; Infectious diseases; Male; Medical sciences; Middle Aged; Minorities; Minority groups; Needle Sharing - adverse effects; Needle-Exchange Programs; One-piece and two-piece syringes; Psychiatry; Psychology. Psychoanalysis. Psychiatry; Psychopathology. Psychiatry; Risk Factors; Substance Abuse, Intravenous - complications; Substance Abuse, Intravenous - epidemiology; Substance Abuse, Intravenous - virology; Syringe cleaning; Syringes; Syringes - adverse effects; Viral diseases; Viral hepatitis; Young Adult; Hungary; Central Europe; Europe; Hungary, Budapest; Syringe cleaning; One-piece and two-piece syringes; Minorities; HCV infection; Central Europe; Human; Drug addiction; Intravenous administration; Hepatic disease; Cleaning; Infection; Association; Addiction; Viral disease; Minority; Syringe; Digestive diseases; Viral hepatitis C
• ISSN: 0376-8716; 1879-0046
• DOI: 10.1016/j.drugalcdep.2008.10.014

Abstract We assessed whether syringe type, syringe cleaning and distributive syringe sharing were associated with self-reported and laboratory-confirmed HCV infection among Hungarian IDUs. Injecting drug users ( N = 215) were recruited from non-treatment settings in Budapest, Hungary between October 2005 and December 2006. Multivariate logistic regression models identified correlates of self-report of being HCV infected and testing positive for HCV. While 37% tested positive for HCV, 14% of the total (39% of those who tested positive) self-reported being HCV infected. Using any two-piece syringes was significantly associated with self-reported HCV infection, while distributive syringe sharing was not associated with self-report of being HCV infected. Engaging in receptive sharing of only one-piece syringes but always cleaning before reuse was not associated with testing HCV positive, while any receptive sharing of only one-piece syringes and not always cleaning before reuse was significantly associated with testing HCV positive. Sharing cookers and squirting drugs from one syringe into another syringe were not associated with testing HCV positive. The high percent of those HCV infected who did not know they were infected highlights the need to provide better access to confidential testing and counseling services. Counseling should emphasize secondary prevention of HCV among HCV infected IDUs. Our findings also indicate that syringe type and syringe cleaning practices may play a role in HCV transmission. Ethnographic research should identify the reasons why IDUs may use two-piece syringes and suggest means to reduce their use. Thorough cleaning of one-piece syringes when sterile syringes are unavailable may be an efficient way to reduce the risk of HCV infection.