Visceral leishmaniasis and arsenic: an ancient poison contributing to antimonial treatment failure in the Indian subcontinent?

• Published in: PLoS neglected tropical diseases Vol. 5; no. 9; p. e1227
• Main Authors: Perry, Meghan R, Wyllie, Susan, Prajapati, Vijay Kumar, Feldmann, Joerg, Sundar, Shyam, Boelaert, Marleen, Fairlamb, Alan H
• Format: Journal Article
• Language: English
• Published: United States Public Library of Science 01.09.2011; Public Library of Science (PLoS)
• Subjects: Antimitotic agents; Antimony - administration & dosage; Antimony - pharmacology; Antineoplastic agents; Antiprotozoal Agents - administration & dosage; Antiprotozoal Agents - pharmacology; Arsenic; Arsenic - metabolism; Biology; Care and treatment; Drug Resistance; Epidemiology; Groundwater; Health aspects; Humans; Hypotheses; India - epidemiology; Kala-azar; Leishmania; Leishmania donovani - drug effects; Leishmania infantum - drug effects; Leishmaniasis, Visceral - drug therapy; Leishmaniasis, Visceral - epidemiology; Malaria; Medicine; Parasites; Parasitic diseases; Poisons; Poisons - metabolism; Protozoa; Treatment Failure; Tropical diseases; Viewpoints; Water, Underground; India; United Kingdom; Bangladesh; Asia; Indian subcontinent; Nepal; Poisons; Antiprotozoal Agents; Leishmania infantum; Arsenic; Humans; Leishmania; Leishmania donovani; Leishmaniasis, Visceral; Treatment Failure; Antimony; Drug Resistance; India
• ISSN: 1935-2735; 1935-2727; 1935-2735
• DOI: 10.1371/journal.pntd.0001227