Downbeat Nystagmus and Bilateral Sudden Hearing Loss by Suicidal Aspirin Intoxication

Ototoxic side effects such as sensorineural hearing loss and tinnitus can be caused by acute salicylate intoxication. Bilateral symmetric sensorineural hearing loss involving all tested frequencies is a typical pattern of hearing loss in acute salicylate intoxication, which usually resolves within 2...

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Bibliographic Details
Published inJournal of International Advanced Otology Vol. 18; no. 4; pp. 378 - 380
Main Authors Noh, Heamin, Lee, Dong-Han, Shin, Jung Eun, Kim, Chang-Hee
Format Journal Article
LanguageEnglish
Published Ankara AVES 01.07.2022
Mediterranean Society for Otology and Audiology
European Academy of Otology and Neurotology and the Politzer Society
Subjects
Anticonvulsants
Aspirin
Binding sites
Case Report
Drug dosages
Ethics
Hearing loss
Hearing protection
Informed consent
Intoxication
Nervous system
Nonprescription drugs
Nystagmus
Suicidal behavior
Suicides & suicide attempts
Tinnitus
Vertigo
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Summary:Ototoxic side effects such as sensorineural hearing loss and tinnitus can be caused by acute salicylate intoxication. Bilateral symmetric sensorineural hearing loss involving all tested frequencies is a typical pattern of hearing loss in acute salicylate intoxication, which usually resolves within 2 or 3 days without any specific treatment for ototoxicity. Herein, we report a case of suicidal aspirin intoxication resulting in sudden bilateral hearing loss and vertigo. The patient exhibited spontaneous downbeat nystagmus, and the mechanism underlying this characteristic nystagmus is discussed.
Bibliography:ORCID IDs of the authors: H.N. 0000-0002-5888-3067; D.-H.L. 0000-0001-9440-9744; J.E.S. 0000-0001-6044-9342; C.-H.K. 0000-0001-5667-861X
Cite this article as: Noh H, Lee D, Shin JE, Kim C. Downbeat nystagmus and bilateral sudden hearing loss by suicidal aspirin intoxication. J Int Adv Otol. 2022;18(4):378-380.
ISSN:1308-7649
2148-3817
DOI:10.5152/iao.2022.21485