Ependymal cells SCOre sweet cerebrospinal fluid

The subcommissural organ (SCO) is a secretory tissue located on the roof of the brain’s third ventricle. A new study published in PLOS Biology finds that the SCO responds to glucose by secreting signaling molecules into the cerebrospinal fluid (CSF), thereby decreasing the local ependyma-driven CSF...

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Bibliographic Details
Published inPLoS biology Vol. 21; no. 9; p. e3002323
Main Authors Liu, Luke L, Fame, Ryann M
Format Journal Article
LanguageEnglish
Published San Francisco Public Library of Science 22.09.2023
Public Library of Science (PLoS)
Subjects
Analysis
Biology and Life Sciences
Blood sugar
Brain
Cerebrospinal fluid
Diabetes
Ependymal cells
Gliomas
Glucose
Homeostasis
Hydrocephalus
Hyperglycemia
Hypothalamus
Investigations
Medicine and Health Sciences
Neurons
Pediatrics
Physical Sciences
Primer
Social Sciences
Subcommissural organ
Ventricle
Ventricles (cerebral)
United States
United States > US
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Summary:The subcommissural organ (SCO) is a secretory tissue located on the roof of the brain’s third ventricle. A new study published in PLOS Biology finds that the SCO responds to glucose by secreting signaling molecules into the cerebrospinal fluid (CSF), thereby decreasing the local ependyma-driven CSF movement.
Bibliography:ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
ObjectType-Commentary-3
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The authors have declared that no competing interests exist.
ISSN:1545-7885
1544-9173
1545-7885
DOI:10.1371/journal.pbio.3002323