Asymptomatic renal BCG granulomatosis: An unusual complication of intravesical BCG therapy for carcinoma urinary bladder

Bacillus Calmette-Guerin (BCG) is considered the most effective adjunctive treatment available to treat superficial bladder carcinoma. Although BCG is well tolerated by most patients, it may be associated with adverse effects. One of these is BCG granulomas in the kidney. We herein report a case of...

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Bibliographic Details
Published inIndian journal of urology Vol. 31; no. 3; pp. 259 - 261
Main Authors Bhat, Suresh, Srinivasa, Yateesh, Paul, Fredrick
Format Journal Article
LanguageEnglish
Published India Medknow Publications 01.07.2015
Medknow Publications and Media Pvt. Ltd
Medknow Publications & Media Pvt. Ltd
Medknow Publications & Media Pvt Ltd
Wolters Kluwer Medknow Publications
Subjects
Adverse drug reactions
BCG
BCG complications
Bladder carcinoma
Case Report
Case studies
Complications and side effects
Granuloma
granulomatous disease
intravesical Bacillus Calmette-Guerin treatment
Kidney diseases
India
intravesical Bacillus Calmette-Guerin treatment
granulomatous disease
Bladder carcinoma
BCG complications
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Summary:Bacillus Calmette-Guerin (BCG) is considered the most effective adjunctive treatment available to treat superficial bladder carcinoma. Although BCG is well tolerated by most patients, it may be associated with adverse effects. One of these is BCG granulomas in the kidney. We herein report a case of a 52-year-old patient who, during a surveillance contrast-enhanced computed tomography (CT) scan, was found to have multiple hypodense lesions in the left kidney. Ultrasound-guided biopsy proved it to be BCG granulomas. After 3 months of anti-tubercular treatment, a repeat CT showed complete resolution of the lesions.
ISSN:0970-1591
1998-3824
DOI:10.4103/0970-1591.156921