Mixed Mycobacterium tuberculosis Lineage Infection in 2 Elephants, Nepal

• Published in: Emerging infectious diseases Vol. 25; no. 5; pp. 1031 - 1032
• Main Authors: Paudel, Sarad, Nakajima, Chie, Mikota, Susan K., Gairhe, Kamal P., Maharjan, Bhagwan, Subedi, Suraj, Poudel, Ajay, Sashika, Mariko, Shimozuru, Michito, Suzuki, Yasuhiko, Tsubota, Toshio
• Format: Journal Article
• Language: English
• Published: United States U.S. National Center for Infectious Diseases 01.05.2019; Centers for Disease Control and Prevention
• Subjects: Animal Diseases - diagnosis; Animal Diseases - epidemiology; Animal Diseases - microbiology; Animals; Bacterial Typing Techniques; China; Elephants; Genes, Bacterial; Health aspects; Humans; India; Japan; lineage; Lineage Infection in 2 Elephants, Nepal; Mycobacterium tuberculosis; Mycobacterium tuberculosis - classification; Mycobacterium tuberculosis - genetics; Mycobacterium tuberculosis - isolation & purification; National parks; Nepal; Nepal - epidemiology; Parks; Research Letter; Sequence Analysis, DNA; Tuberculosis; Tuberculosis - veterinary; tuberculosis and other mycobacteria; Nepal; Japan; China; India; lineage; Mycobacterium tuberculosis; bacteria; tuberculosis; elephants; tuberculosis and other mycobacteria; zoonoses; Nepal; TB
• ISSN: 1080-6040; 1080-6059; 1080-6059
• DOI: 10.3201/eid2505.181898

Tuberculosis in elephants is primarily caused by Mycobacterium tuberculosis. We identified mixed M. tuberculosis lineage infection in 2 captive elephants in Nepal by using spoligotyping and large sequence polymorphism. One elephant was infected with Indo-Oceanic and East African-Indian (CAS-Delhi) lineages; the other was infected with Indo-Oceanic and East Asian (Beijing) lineages.