Long-term graft patency after coronary artery bypass grafting: Effects of surgical technique

• Published in: Experimental and therapeutic medicine Vol. 17; no. 1; pp. 359 - 367
• Main Authors: Tinica, Grigore, Chistol, Raluca Ozana, Bulgaru Iliescu, Diana, Furnica, Cristina
• Format: Journal Article
• Language: English
• Published: Greece Spandidos Publications 01.01.2019; Spandidos Publications UK Ltd; D.A. Spandidos
• Subjects: Analysis; Angioplasty; Cardiovascular disease; Cardiovascular diseases; Causes of; Complications and side effects; Confidence intervals; Coronary artery bypass; Coronary vessels; Heart surgery; Patients; Standard deviation; Surgical anastomosis; Surgical techniques; Variables; Romania; anastomosis type; long-term patency; anastomosis angle; composite grafting; coronary artery bypass grafting
• ISSN: 1792-0981; 1792-1015
• DOI: 10.3892/etm.2018.6929

The aim of the current study was to identify surgical factors associated with long-term patency of grafts used in coronary artery bypass grafting (CABG). The present study analyzed data from 127 patients who underwent CABG at our institute between 2000 and 2006 and presented for ambulatory examination and coronary computed tomography angiography evaluation of graft patency in 2016 (139.78±36.64 months post-CABG). The 127 patients received 340 grafts (2.68 grafts/patient) and 399 distal anastomoses (3.14 anastomoses/patient), 220 (55.14%) with arterial grafts and 179 (44.86%) with saphenous vein grafts. Graft patency varied according to coronary territory, proximal anastomosis type ( graft, composite graft, graft anastomosed to the ascending aorta), Y anastomosis angle (47.21° for patent arterial grafts vs. 56° for occluded), and distal anastomosis angle (in sequential anastomoses irrespective to graft type, 48.60° for patent side-to-side anastomosis vs. 53.97° for occluded, 65.12° for patent end-to-side anastomosis vs. 90.80° for occluded; in single end-to-side anastomosis of arterial grafts, 39.46° for patent and 44.94° for occluded). A single end-to-side anastomosis angle 60° or greater was associated with a 5.149 occlusion odds ratio (OR) (P<0.001) for arterial grafts. Venous grafts were not sensitive to single end-to-side anastomosis angle. In conclusion, a small anastomosis angle for proximal Y and distal anastomoses is associated with a higher long-term patency of the free graft. Radial artery grafts registered higher patency rates when anastomosed to the ascending aorta compared with composite grafting with the left internal thoracic artery, whereas right internal thoracic artery (RITA) anastomosed to the right coronary territory is associated with a lower patency rate compared with free RITA used to revascularise the anterolateral or circumflex territory in composite grafting.