Quercetin attenuates neuronal cells damage in a middle cerebral artery occlusion animal model

• Published in: Journal of Veterinary Medical Science Vol. 80; no. 4; pp. 676 - 683
• Main Authors: PARK, Dong-Ju, SHAH, Fawad-Ali, KOH, Phil-Ok
• Format: Journal Article
• Language: English
• Published: Japan JAPANESE SOCIETY OF VETERINARY SCIENCE 01.04.2018; Japan Science and Technology Agency; The Japanese Society of Veterinary Science
• Subjects: Apoptosis; Caspase; Caspase-3; Cerebral blood flow; Edema; Inflammation; Ischemia; Laboratory Animal Science; Neurodegeneration; Neuroprotection; PARP; Poly(ADP-ribose) polymerase; Quercetin; Ribose; Rodents; Triphenyltetrazolium chloride; Vegetables; quercetin; PARP; neuroprotection; caspase-3

Cerebral ischemia is a neurological disorder with high mortality. Quercetin is a flavonoid compound that is abundant in vegetables and fruits. It exerts anti-inflammatory and anti-apoptotic effects. This study investigated the neuroprotective effects of quercetin in focal cerebral ischemia. Male Spr...