Adaptive pathways of zoonotic influenza viruses: From exposure to establishment in humans
Highlights ► Pandemic influenza viruses all have their origins in animal reservoirs. ► Adaptive changes characterize animal influenza viruses crossing species barriers. ► These changes have been mapped to genetic mutations and specific adaptive pathways. ► These mutations and adaptive pathways are t...
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Published in | Vaccine Vol. 30; no. 30; pp. 4419 - 4434 |
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Main Authors | , , |
Format | Journal Article |
Language | English |
Published |
Netherlands
Elsevier Ltd
22.06.2012
Elsevier Limited |
Subjects | |
Online Access | Get full text |
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Summary: | Highlights ► Pandemic influenza viruses all have their origins in animal reservoirs. ► Adaptive changes characterize animal influenza viruses crossing species barriers. ► These changes have been mapped to genetic mutations and specific adaptive pathways. ► These mutations and adaptive pathways are the subject of this review. |
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Bibliography: | http://dx.doi.org/10.1016/j.vaccine.2012.04.049 ObjectType-Article-2 SourceType-Scholarly Journals-1 ObjectType-Feature-3 content type line 23 ObjectType-Review-1 ObjectType-Feature-1 |
ISSN: | 0264-410X 1873-2518 |
DOI: | 10.1016/j.vaccine.2012.04.049 |