Regression of Hodgkin Lymphoma in Response to Antiviral Therapy for Hepatitis C Virus Infection

Links between hepatitis C virus (HCV) infection and several non-Hodgkin lymphomas have been suggested by epidemiological studies. We herein report the first documented case of a patient with HCV-associated Hodgkin lymphoma who showed a marked regression following interferon-based antiviral therapy....

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Bibliographic Details
Published inInternal Medicine Vol. 51; no. 19; pp. 2745 - 2747
Main Authors Takahashi, Ken, Nishida, Naoshi, Kawabata, Hiroshi, Haga, Hironori, Chiba, Tsutomu
Format Journal Article
LanguageEnglish
Published Japan The Japanese Society of Internal Medicine 01.01.2012
Subjects
Antiviral Agents - therapeutic use
Hepatitis C virus
Hepatitis C, Chronic - complications
Hepatitis C, Chronic - drug therapy
Hodgkin Disease - complications
Hodgkin Disease - diagnostic imaging
Hodgkin Disease - drug therapy
Hodgkin Disease - pathology
Hodgkin lymphoma
Humans
interferon
Interferon-alpha - therapeutic use
Male
Middle Aged
Polyethylene Glycols - therapeutic use
Recombinant Proteins - therapeutic use
Remission Induction
Ribavirin - therapeutic use
Tomography, X-Ray Computed
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Summary:Links between hepatitis C virus (HCV) infection and several non-Hodgkin lymphomas have been suggested by epidemiological studies. We herein report the first documented case of a patient with HCV-associated Hodgkin lymphoma who showed a marked regression following interferon-based antiviral therapy. This unique case extends the spectrum of HCV-associated malignant lymphomas, confirms the efficacy of antiviral therapy for this rare extrahepatic manifestation and provides valuable clues for achieving a better understanding of lymphomagenesis in HCV.
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ISSN:0918-2918
1349-7235
DOI:10.2169/internalmedicine.51.8404