Recent Developments in the Trifluoromethylation of Alkynes

• Published in: Chemistry : a European journal Vol. 21; no. 21; pp. 7648 - 7661
• Main Authors: Gao, Pin, Song, Xian-Rong, Liu, Xue-Yuan, Liang, Yong-Min
• Format: Journal Article
• Language: English
• Published: Weinheim WILEY-VCH Verlag 18.05.2015; WILEY‐VCH Verlag; Wiley Subscription Services, Inc
• Subjects: alkyne; Alkynes; Alkynes - chemical synthesis; Alkynes - chemistry; Catalysis; Chemistry; Chemistry Techniques, Synthetic - methods; Construction; Covering; difunctionalization; Formations; Halogenation; Hydrocarbons, Fluorinated - chemical synthesis; Hydrocarbons, Fluorinated - chemistry; Methylation; radical reactions; Radicals; synthetic methods; trifluoromethylation; radical reactions; difunctionalization; alkyne; trifluoromethylation; synthetic methods

In the last few years, the development of versatile methodologies to incorporate trifluoromethyl groups into organic molecules has attracted significant attention in synthetic chemistry. This review gives an overview over the development on the trifluoromethylation of alkynes, which have not been so...