正常成人脑部皮层下灰质结构的3D pc-ASL灌注成像的可重复性

目的研究正常成人脑部皮层下灰质结构3D假连续快速自旋回波动脉自旋标记（3D pc-ASL）灌注的可重复性。方法对8例健康成年人进行脑部3D pc-ASL序列及3D结构像扫描,同一时间间隔一周后再次进行扫描。对3D结构像进行皮层下灰质结构（壳核、苍白球、尾状核、丘脑、杏仁核、海马）分割,并将3D pc-ASL进行计算生成脑血流（CBF）图,基于分割后的图像及CBF图进行皮层下灰质结构CBF值提取。对于两次测量结果采用组内相关系数（ICC）及Bland-Altman图分析。结果皮层下灰质结构的ICC值为0.80-0.93,均值为0.88±0.04。Bland-Altman图形分析证实所有皮层下灰质...

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Published in南方医科大学学报 Vol. 37; no. 9; pp. 1242 - 1247
Main Author 刘梦琦 陈志晔 马林
Format Journal Article
LanguageChinese
Published 中国人民解放军总医院放射科,北京100853%中国人民解放军总医院放射科,北京,100853 2017
中国人民解放军总医院海南分院放射科,海南三亚572013
Subjects
动脉自旋标记
皮层下灰质
磁共振成像
组内相关系数
脑
脑
magnetic resonance imaging
皮层下灰质
磁共振成像
subcortical gray matter
intraclass correlation
动脉自旋标记
组内相关系数
brain
arterial spin labeling
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Summary:目的研究正常成人脑部皮层下灰质结构3D假连续快速自旋回波动脉自旋标记（3D pc-ASL）灌注的可重复性。方法对8例健康成年人进行脑部3D pc-ASL序列及3D结构像扫描,同一时间间隔一周后再次进行扫描。对3D结构像进行皮层下灰质结构（壳核、苍白球、尾状核、丘脑、杏仁核、海马）分割,并将3D pc-ASL进行计算生成脑血流（CBF）图,基于分割后的图像及CBF图进行皮层下灰质结构CBF值提取。对于两次测量结果采用组内相关系数（ICC）及Bland-Altman图分析。结果皮层下灰质结构的ICC值为0.80-0.93,均值为0.88±0.04。Bland-Altman图形分析证实所有皮层下灰质结构对应的点均位于95%一致性界限内。结论 3D pc-ASL是一个可靠的评估脑部皮层下灰质核团灌注的序列。
Bibliography:44-1627/R
arterial spin labeling; brain; intraclass correlation; magnetic resonance imaging; subcortical gray matter
LIU Mengqi1,2, CHEN Zhiye1,2, MA Lin2 （1Department of Radiology, Hainan Branch of General Hospital of PLA, Sanya 572013, China; 2Department of Radiology, General Hospital of PLA, Beijing 100853, China）
Objective To evaluate the test-retest reliability of 3D spiral fast-spin-echo （FSE） pseudo-continuous arterial spin labeling （3D pc-ASL） for cerebral perfusion imaging of the subcortical gray matter in healthy adults in resting state.Methods3 D spiral FSE ASL and 3D T1-weighted fast spoiled gradient recalled echo （3D T1-FSPGR） sequences were used for cerebral perfusion imaging in 8 healthy adult subjects,and a repeat imaging examination was performed after one week.The subcortical gray matter structures including the putamen,globus pallidus,caudate nucleus,thalamus,amygdala and hippocampus were segmented on the brain structural 3D images to generate the cerebral blood flow （CBF） map.The CBF value wa
ISSN:1673-4254
DOI:10.3969/j.issn.1673-4254.2017.09.17