中老年男性人群维生素D水平及其与肌力、跌倒风险的研究

目的探讨中老年男性人群维生素D（VD）营养状况及其与肌力、跌倒风险的关系。方法横断面调查,分析某40岁以上查体人群增龄、VD水平与肌力及跌倒风险之间的关系。结果该人群维生素D缺乏占77.41%,其中严重缺乏占7.83%。随增龄,握力、指捏力、下肢肌力逐渐下降,站起步行试验（TGUT）时间、站起试验（CRT）时间及异常率增加,差异有统计学意义。各年龄组维生素D水平在校正摄入奶量、日照时间、运动频率、工作环境等因素后,差异无统计学意义。按维生素D水平分组比较,只有握力及指捏力在严重缺乏组与其他组间差异达到统计学意义。但在校正年龄影响后,血钙水平、握力、指捏力、下肢肌力在组间差异有统计学意义,维生素...

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Published in中国骨质疏松杂志 Vol. 22; no. 2; pp. 154 - 158
Main Author 王琪 刘敏燕 李春霖 张丽丽 李楠 孙般若 马丽超 祖源 胡帆
Format Journal Article
LanguageChinese
Published 解放军总医院老年内分泌科,北京,100853 2016
Subjects
男性
维生素D
肌力
跌倒
肌力
维生素D
Muscle strength
Vitamin D
跌倒
Male
Fall
男性
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Summary:目的探讨中老年男性人群维生素D（VD）营养状况及其与肌力、跌倒风险的关系。方法横断面调查,分析某40岁以上查体人群增龄、VD水平与肌力及跌倒风险之间的关系。结果该人群维生素D缺乏占77.41%,其中严重缺乏占7.83%。随增龄,握力、指捏力、下肢肌力逐渐下降,站起步行试验（TGUT）时间、站起试验（CRT）时间及异常率增加,差异有统计学意义。各年龄组维生素D水平在校正摄入奶量、日照时间、运动频率、工作环境等因素后,差异无统计学意义。按维生素D水平分组比较,只有握力及指捏力在严重缺乏组与其他组间差异达到统计学意义。但在校正年龄影响后,血钙水平、握力、指捏力、下肢肌力在组间差异有统计学意义,维生素D严重缺乏组最低。在60岁以上组,CRT时间在维生素D缺乏组最长,组间差异有统计学意义。但TGUT在各年龄亚组,三组维生素D水平组间差异均未达到统计学意义。logistic多元逐步回归显示,增龄、握力减低与维生素D缺乏独立相关,OR值分别为1.37和1.33。结论 40岁以上男性维生素D缺乏比例较高,随增龄肌力下降、跌倒风险增高,增龄、上肢肌力减退是维生素D缺乏的独立影响因素。
Bibliography:Objective To investigate the relationship among muscle strength, fall risk, and vitamin D （VD） status in the middle- aged and elderly males. Methods A cross-sectional survey was designed. Changes of VD with age and its relationship with muscle strength and fall risk were observed. Results The VD deficiency rate accounted for 77.41% , including 7.83 % serious deficiency in the group. With the increase of age, the grip and pinch strength and muscle strength of the lower, limbs decreased gradually. The time of get-up and go test （TGUT） and chair rising test （CRT） increased. After adjusting milk intake, sunshine duration, exercise frequency, and working environment, there was no significant difference in the level of VD among groups by age. Grip and pinch strength decreased in serious VD deficiency group. After adjusting age, the difference of serum calcium, grip and pinch strength, and muscle strength of the lower limbs among groups was significant. And the lowest level was found in the serious VD deficiency gro
ISSN:1006-7108
DOI:10.3969/j.issn.1006-7108.2016.02.007