认知灵活性的神经动力学：事件相关电位时空模式分析

目的探索认知灵活性相关脑网络的动态演化。方法采用交替切换任务范式,23名被试完成数字大小和奇偶判断任务,每3个试次数字颜色改变,提示任务规则切换,3个试次分别对应切换、基线和准备条件。分析3种条件下的行为绩效和19通道事件相关电位统计参数映像的时空模式。结果切换代价（切换-基线）显著：反应时123.61±83.84 ms;正确率（1.24±3.30）%。事件相关电位统计参数映像（t）显示：切换效应先后出现在额顶网络的右侧和左侧部分,准备效应主要表现为反应前右侧额极和反应后左侧额极的激活。结论认知灵活性主要依赖于额顶网络的动态激活,而前额极参与任务切换前的跨试次准备过程;背侧额区参与试次内的即时...

Full description

Saved in:
Bibliographic Details
Published in南方医科大学学报 Vol. 37; no. 6; pp. 755 - 760
Main Author 曹园 周曙 王优
Format Journal Article
LanguageChinese
Published 南方医科大学南方医院神经内科,广东 广州,510515%南方医科大学公共卫生学院心理学系,广东 广州,510515 2017
Subjects
事件相关电位
交替切换
准备效应
切换代价
认知灵活性
alternating runs
事件相关电位
switch cost
切换代价
交替切换
preparation effect
准备效应
event-related potentials
cognitive flexibility
认知灵活性
Online AccessGet full text
ISSN1673-4254
DOI10.3969/j.issn.1673-4254.2017.06.07

Cover

More Information
Summary:目的探索认知灵活性相关脑网络的动态演化。方法采用交替切换任务范式,23名被试完成数字大小和奇偶判断任务,每3个试次数字颜色改变,提示任务规则切换,3个试次分别对应切换、基线和准备条件。分析3种条件下的行为绩效和19通道事件相关电位统计参数映像的时空模式。结果切换代价（切换-基线）显著：反应时123.61±83.84 ms;正确率（1.24±3.30）%。事件相关电位统计参数映像（t）显示：切换效应先后出现在额顶网络的右侧和左侧部分,准备效应主要表现为反应前右侧额极和反应后左侧额极的激活。结论认知灵活性主要依赖于额顶网络的动态激活,而前额极参与任务切换前的跨试次准备过程;背侧额区参与试次内的即时任务切换,且左右两侧额区功能不同。
Bibliography:44-1627/R
Objective To explore the neural dynamics during alternating task switching. Methods In an alternating-runs paradigm, 23 healthy volunteers were asked to categorize Arabic numerals displayed on the screen into either even or odd numbers or judge if the number was greater than 5 according its color cues. The color of the numerals were regularly switched every three trials （switch, nested and pre-switch trials）. ANOVA of repeated-measure and paired t-test were used for analysis of the behavioral performance and event-related potential （ERP） data of 19 channels, and statistical parametric mapping of F and t values was used to reveal the spatiotemporal patterns of ERP. Results Significant switch costs （switch versus nested trial） were found in the mean reaction time （123.61 ＆#177; 83.84 ms, P〈0.05） and the mean accuracy [（1.24 ＆#177; 3.30）%, P〈0.05]. Statistical parametric mapping of t value of ERP suggested that the switch effects appeared in the right frontal-parietal network and then in the left one. T
ISSN:1673-4254
DOI:10.3969/j.issn.1673-4254.2017.06.07