Visualizing Dynamic Performance of Lipid Droplets in a Parkinson’s Disease Model via a Smart Photostable Aggregation-Induced Emission Probe

• Published in: iScience Vol. 21; pp. 261 - 272
• Main Authors: Li, Lihua, Zhou, Fan, Gao, Qun, Lu, Yao, Xu, Xingyi, Hu, Rong, Wang, Zhiming, Peng, Mingying, Yang, Zhongmin, Tang, Ben Zhong
• Format: Journal Article
• Language: English
• Published: United States Elsevier Inc 22.11.2019; Elsevier BV; Elsevier
• Subjects: Chemical Synthesis; Disease; Materials Design; Q; Science; Disease; Chemical Synthesis; Materials Design

Parkinson’s disease (PD) is a complex neurodegenerative disease affected by diverse factors, and lipid droplets (LDs) are increasingly recognized as major players in PD because of their relevance to neuron activity. However, long-term dynamic changes of LDs and their relative activity remain unclear...