Datasets of YY1 expression in rheumatoid arthritis patients

The data presented in this article are related to the research article entitled “A critical role of transcription factor YY1 in rheumatoid arthritis by regulation of interleukin-6” (J. Lin, Y. He, J. Chen, Z. Zeng, B. Yang, Q. Ou, 2016) [1]. The article describes YY1 overexpression is specific for R...

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Bibliographic Details
Published inData in brief Vol. 9; no. C; pp. 1034 - 1038
Main Authors Lin, Jinpiao, He, Yujue, Chen, Junmin, Zeng, Zhiyong, Bin Yang, Ou, Qishui
Format Journal Article
LanguageEnglish
Published Netherlands Elsevier Inc 01.12.2016
Elsevier
Subjects
blood serum
CRP
Data
data collection
ESR
Interleukin-6
Rheumatoid arthritis
risk
therapeutics
transcription factors
CRP
ESR
Rheumatoid arthritis
Interleukin-6
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Summary:The data presented in this article are related to the research article entitled “A critical role of transcription factor YY1 in rheumatoid arthritis by regulation of interleukin-6” (J. Lin, Y. He, J. Chen, Z. Zeng, B. Yang, Q. Ou, 2016) [1]. The article describes YY1 overexpression is specific for RA, but not for SLE, SS, DM or MCTD. In early RA, YY1 expression is also increased. In asymptomatic subjects with RF or ACPA positive who have high risk for developing RA, the YY1 expression is not increased obviously. Moreover, YY1 expression is positively correlated with serum CRP or ESR. In RA patients treated with anti-IL-6R monoclonal Ab tocilizumab, there is no significant difference in YY1 expression after IL-6 blocking therapy.
Bibliography:ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 23
ISSN:2352-3409
2352-3409
DOI:10.1016/j.dib.2016.11.046