Evaluation of antibacterial activity of Achyranthes aspera extract against Streptococcus mutans: An in vitro study

• Published in: Journal of advanced pharmaceutical technology and research Vol. 7; no. 4; pp. 149 - 152
• Main Authors: Yadav, Roma, Rai, Radhika, Yadav, Abhishek, Pahuja, Meetika, Solanki, Savita, Yadav, Himani
• Format: Journal Article
• Language: English
• Published: India Wolters Kluwer India Pvt. Ltd 01.10.2016; Medknow Publications and Media Pvt. Ltd; Medknow Publications & Media Pvt. Ltd; Medknow Publications & Media Pvt Ltd; Wolters Kluwer Medknow Publications
• Subjects: Achyranthes aspera; Analysis; Antibacterial activity; Antibacterial agents; Antimicrobial agents; apamarga; Bacteria; chlorhexidine; Dental caries; Disease prevention; Drugs; Herbal medicine; Microorganisms; Original; Periodontal diseases; Statistical analysis; Streptococcus infections; Streptococcus mutans; Studies; antibacterial activity; apamarga; chlorhexidine; Achyranthes aspera; Streptococcus mutans
• ISSN: 2231-4040; 0976-2094
• DOI: 10.4103/2231-4040.191426

Dental caries and periodontal diseases have historically been considered the most important global oral health burdens. Many chemicals and synthetic drugs have marked the side effects. Hence, there has been a paradigm shift from the use of modern drugs to the age-old herbs. Achyranthes aspera is one such important plant with various established pharmaceutical properties. The aim of this study was to assess the antibacterial activity of the A. aspera extract against Streptococcus mutans. Aqueous extract of A. aspera was prepared. Different concentrations of the root and stem extracts of A. aspera were transferred to the agar plates, which had been streaked with the bacterium S. mutans. The plates were incubated aerobically at 37°C for 24 h, and the zones of inhibition were measured using cup plate method. A. aspera extract showed statistically significant zones of inhibition. A. aspera showed marked antibacterial activity against S. mutans.