When is a varicocele repair indicated： the dilemma of hypogonadism and erectile dysfunction

In the past, the indications for varicocelectomy are primarily for infertility with abnormal semen parameters, testicular hypotrophy/atrophy in adolescents, and/or pain. The surgical treatment of varicocele for hypogonadism is controversial and debated. Recently, multiple reports in the literature h...

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Bibliographic Details
Published inAsian journal of andrology Vol. 18; no. 2; pp. 213 - 216
Main Authors Dabaja, Ali A, Goldstein, Marc
Format Journal Article
LanguageEnglish
Published China Medknow Publications and Media Pvt. Ltd 01.03.2016
Medknow Publications & Media Pvt. Ltd
Medknow Publications & Media Pvt Ltd
Wolters Kluwer Medknow Publications
Subjects
Androgens
Biosynthesis
Care and treatment
Chronic illnesses
Erectile Dysfunction - etiology
erectile dysfunction; hypogonadism; varicocele; varicocelectomy
Humans
Hypogonadism
Hypogonadism - etiology
Impotence
Infertility
Invited Review
Male
Proteins
Rodents
Sexual disorders
Spermatogenesis
Studies
Testosterone
Testosterone - blood
Varicocele
Varicocele - complications
Varicocele - surgery
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Summary:In the past, the indications for varicocelectomy are primarily for infertility with abnormal semen parameters, testicular hypotrophy/atrophy in adolescents, and/or pain. The surgical treatment of varicocele for hypogonadism is controversial and debated. Recently, multiple reports in the literature have suggested that varicocele is associated with hypogonadism and varicocele repair can increase testosterone levels. Men with hypogonadal symptoms should have at least two serum testosterone levels. Microsurgical varicocelectomy may be beneficial for men with clinically palpable varicoceles with documented hypogonadism. In this review, we summarize the most recent literature linking varicocele to hypogonadism and sexual dysfunction and the impact of repair on serum testosterone levels. We performed a search of the published English literature. The key words used were ＂varicocele and hypogonadism＂ and ＂varicocele surgery and testosterone.＂ We included published studies after 1998. We, also, evaluated the effect of surgery on the changes in the serum testosterone level regardless of the indication for the varicocele repair.
Bibliography:erectile dysfunction; hypogonadism; varicocele; varicocelectomy
In the past, the indications for varicocelectomy are primarily for infertility with abnormal semen parameters, testicular hypotrophy/atrophy in adolescents, and/or pain. The surgical treatment of varicocele for hypogonadism is controversial and debated. Recently, multiple reports in the literature have suggested that varicocele is associated with hypogonadism and varicocele repair can increase testosterone levels. Men with hypogonadal symptoms should have at least two serum testosterone levels. Microsurgical varicocelectomy may be beneficial for men with clinically palpable varicoceles with documented hypogonadism. In this review, we summarize the most recent literature linking varicocele to hypogonadism and sexual dysfunction and the impact of repair on serum testosterone levels. We performed a search of the published English literature. The key words used were ＂varicocele and hypogonadism＂ and ＂varicocele surgery and testosterone.＂ We included published studies after 1998. We, also, evaluated the effect of surgery on the changes in the serum testosterone level regardless of the indication for the varicocele repair.
31-1795/R
ObjectType-Article-2
SourceType-Scholarly Journals-1
ObjectType-Feature-3
content type line 23
ObjectType-Review-1
ISSN:1008-682X
1745-7262
DOI:10.4103/1008-682X.169560