PRODUCTION OF VERNAMYCIN BY A MICROMONOSPORA

While not uncommon to find the same or a closely related antibiotic produced by members of two different taxonomic families, it is less than common to find an antibiotic produced by three or more such taxonomic groups. A few examples of such biosynthetic diversity reported in the literature are: bet...

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Published inJournal of antibiotics Vol. 34; no. 11; pp. 1515 - 1516
Main Authors LIU, WEN-CHIH, SEINER, VERA, DEAN, LORETTA D., TREJO, WILLIAM H., PRINCIPE, PACIFICO A., MEYERS, EDWARD, SYKES, RICHARD B.
Format Journal Article
LanguageEnglish
Published Japan JAPAN ANTIBIOTICS RESEARCH ASSOCIATION 01.01.1981
Subjects
Chemical Phenomena
Chemistry
Drug Synergism
Fermentation
Micromonospora
Micromonospora - metabolism
Virginiamycin - biosynthesis
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Summary:While not uncommon to find the same or a closely related antibiotic produced by members of two different taxonomic families, it is less than common to find an antibiotic produced by three or more such taxonomic groups. A few examples of such biosynthetic diversity reported in the literature are: beta -lactam production by bacteria, actinomycetes (Streptomyces and Nocardia ) and fungi; actinomycin production by streptomycetes, Actinoplanes and Micromonospora ; and erythromycin production by a bacterium, streptomycetes and Micromonospora . In this communication, the authors present evidence for the addition of Micromonospora to the list of diverse microorganisms capable of synthesizing vernamycins. Previously reported to synthesize members of this antibiotic group are streptomycetes, Actinoplanes and Actinomadura .
Bibliography:ObjectType-Article-2
SourceType-Scholarly Journals-1
ObjectType-Feature-1
content type line 23
ISSN:0021-8820
1881-1469
DOI:10.7164/antibiotics.34.1515