Effects of Exercise Therapy on Heat Shock Protein70 Expression in Leukocytes

• Published in: Journal of Physical Therapy Science Vol. 22; no. 3; pp. 307 - 310
• Main Authors: Han, Gunsoo, Ko, Taesung, Cho, Minhaeng, Cho, Byungjun
• Format: Journal Article
• Language: English
• Published: The Society of Physical Therapy Science 2010
• Subjects: Exercise therapy; Heat Shock Protein70; Leukocytes
• ISSN: 0915-5287; 2187-5626
• DOI: 10.1589/jpts.22.307

[Purpose] The purpose of this study was to identify effects of exercise therapy on Heat Shock Protein (HSP70) in obese individuals. [Subjects] This study compared pre- and post-intervention levels of HSP70 between two obesity groups (obese exercise therapy n=7, obese control n=7). [Methods] Exercise therapy subjects were treated on a treadmill for 50 minutes at 55-80% of maximal heart rate for eight weeks. The HSP levels were measured prior to exercise at rest, exhaustion and 30 minutes after exercise therapy. Baseline HSP levels were also measured in seven controls, at rest, exhaustion and 30 minutes after exercise therapy. [Results] The findings show HSP levels in the long-term exercise therapy subjects were significantly lower than those of the control group at exhaustion. In this study, HSP70 levels may have increased significantly after exercise. [Conclusion] We conclude that the lower levels of baseline HSP70 expression in exercise therapy subjects might be the results of chronic adaptation to training.