Cancer Stem Cell Markers for Urinary Carcinoma

Cancer stem cell (CSC) refers to cancer cells with stem cell properties, that is, they have the ability of “self-renewal” and “differentiation.” Cancer stem cells exist in cancer cells and are the “culprit” of cancer recurrence and metastasis. It is difficult to be found because of its small amount,...

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Published inStem cells international Vol. 2022; pp. 1 - 7
Main Authors Xia, Pu, Liu, Da-Hua, Xu, Ze-Jun, Ren, Fu
Format Journal Article
LanguageEnglish
Published United States Hindawi 15.03.2022
John Wiley & Sons, Inc
Wiley
Subjects
Androgens
Anticancer properties
Antineoplastic drugs
Antitumor agents
Biomarkers
Cancer
Care and treatment
Cell differentiation
Cell self-renewal
Cell surface
Chemotherapy
Dehydrogenases
Diagnosis
Health aspects
Metastases
Metastasis
Oncology
Prostate cancer
Proteins
Radiation therapy
Review
Signal transduction
Solid tumors
Stem cells
Surface markers
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Summary:Cancer stem cell (CSC) refers to cancer cells with stem cell properties, that is, they have the ability of “self-renewal” and “differentiation.” Cancer stem cells exist in cancer cells and are the “culprit” of cancer recurrence and metastasis. It is difficult to be found because of its small amount, and it is difficult for anticancer drugs to produce effects on it. At present, the isolation and identification of cancer stem cells from many solid tumors are still quite difficult, mainly due to the lack of specific molecular markers of cancer stem cells. In this review, cancer stem cell surface markers and functional markers in urinary system were summarized. These markers can provide molecular targets for cancer therapy.
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Academic Editor: Valeria Sorrenti
ISSN:1687-966X
1687-9678
1687-9678
DOI:10.1155/2022/3611677