The vascular health status of a population of adult Canadian Indigenous peoples from British Columbia

• Published in: Journal of human hypertension Vol. 30; no. 4; pp. 278 - 284
• Main Authors: Foulds, H J A, Bredin, S S D, Warburton, D E R
• Format: Journal Article
• Language: English
• Published: England Nature Publishing Group 01.04.2016
• Subjects: Adult; Age Factors; Baroreflex; Blood Pressure; Body Composition; British Columbia; Canadian native peoples; Cardiovascular diseases; Care and treatment; Carotid Intima-Media Thickness; Compliance; Demographic aspects; Diagnosis; Female; Health aspects; Health Status; Humans; Hypertension; Indians, North American; Indigenous peoples; Life Style - ethnology; Male; Middle Aged; Older people; Physiological aspects; Pulse Wave Analysis; Risk Factors; Sex Factors; Statistics; Structure-function relationships; Vascular Diseases - diagnosis; Vascular Diseases - ethnology; Vascular Diseases - physiopathology; Vascular Stiffness; Young Adult; British Columbia
• ISSN: 0950-9240; 1476-5527
• DOI: 10.1038/jhh.2015.51

Indigenous populations currently experience greater cardiovascular disease burdens. However, subclinical vascular structure and function among these populations is not well known. This investigation evaluated vascular structure and function among Canadian Indigenous populations. Blood pressure, body composition, pulse-wave velocity (PWV), baroreceptor sensitivity (BRS), arterial compliance and intima-media thickness (IMT) were measured. Vascular measures were evaluated across sexes and age groups. Vascular assessments were conducted among 55 Indigenous adults (38±18 years, 29 Female), including both First Nations (N=36) and Métis (N=19) individuals. Some differences in vascular measures were found between males and females, respectively (spectral BRS: 9.6±6.8 ms mm Hg(-1) vs 16.9±10.0 ms mm Hg(-1), P=0.01; small arterial compliance: 8.9±3.7 ml mm Hg(-1) × 100 vs 6.4±2.3 ml mm Hg(-1) × 100, P=0.004), with similar measures of overall IMT (0.61±0.14 mm vs 0.57±0.08 mm, P=0.19) and central PWV (5.7±2.5 m s(-1) vs 5.1±2.3 m s(-1), P=0.58). Greater IMT, and lower BRS and arterial compliance were identified among older adults. This relatively healthy population demonstrated healthy vascular measures, with poorer measures among older individuals.