Effects of repetitive transcranial magnetic stimulation on clinical, social, and cognitive performance in postpartum depression

This randomized, placebo-controlled, double-blind pilot study evaluated the impact of repetitive transcranial magnetic stimulation (rTMS) on clinical, cognitive, and social performance in women suffering with postpartum depression. Fourteen patients were randomized to receive 20 sessions of sham rTM...

Full description

Saved in:
Bibliographic Details
Published inNeuropsychiatric disease and treatment Vol. 8; no. default; pp. 491 - 500
Main Authors Myczkowski, Martin Luiz, Dias, Alvaro Machado, Luvisotto, Tatiana, Arnaut, Debora, Bellini, Bianca Boura, Mansur, Carlos Gustavo, Rennó, Joel, Tortella, Gabriel, Ribeiro, Philip Leite, Marcolin, Marco Antônio
Format Journal Article
LanguageEnglish
Published New Zealand Dove Medical Press Limited 01.01.2012
Taylor & Francis Ltd
Dove Press
Dove Medical Press
Subjects
clinical performance
Cognition
Cognitive ability
cognitive performance
Demographic aspects
Magnetic brain stimulation
Mental depression
Original Research
Postpartum depression
social performance
Statistics
Transcranial magnetic stimulation
social performance
clinical performance
postpartum depression
transcranial magnetic stimulation
cognitive performance
Online AccessGet full text

Cover

More Information
Summary:This randomized, placebo-controlled, double-blind pilot study evaluated the impact of repetitive transcranial magnetic stimulation (rTMS) on clinical, cognitive, and social performance in women suffering with postpartum depression. Fourteen patients were randomized to receive 20 sessions of sham rTMS or active 5 Hz rTMS over the left dorsolateral prefrontal cortex. Psychiatric clinical scales and a neuropsychological battery were applied at baseline (pretreatment), week 4 (end of treatment), and week 6 (follow-up, posttreatment week 2). The active rTMS group showed significant improvement 2 weeks after the end of rTMS treatment (week 6) in Hamilton Depression Rating Scale (P = 0.020), Global Assessment Scale (P = 0.037), Clinical Global Impression (P = 0.047), and Social Adjustment Scale-Self Report-Work at Home (P = 0.020). This study suggests that rTMS has the potential to improve the clinical condition in postpartum depression, while producing marginal gains in social and cognitive function.
Bibliography:ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 23
ISSN:1176-6328
1178-2021
1176-6328
DOI:10.2147/NDT.S33851