Transanal total mesorectal excision for low rectal cancer: a case-matched study comparing TaTME versus standard laparoscopic TME

• Published in: Cancer management and research Vol. 10; pp. 5239 - 5245
• Main Authors: Rubinkiewicz, Mateusz, Nowakowski, Michał, Wierdak, Mateusz, Mizera, Magdalena, Dembiński, Marcin, Pisarska, Magdalena, Major, Piotr, Małczak, Piotr, Budzyński, Andrzej, Pędziwiatr, Michał
• Format: Journal Article
• Language: English
• Published: New Zealand Dove Medical Press Limited 01.01.2018; Taylor & Francis Ltd; Dove Medical Press
• Subjects: Analysis; Cancer research; Cancer surgery; Care and treatment; Clinical trials; Colorectal cancer; Colorectal surgery; Laparoscopic TME; Laparoscopy; low rectal cancer; minimally invasive surgery; Morbidity; Mortality; NMR; Novels; Nuclear magnetic resonance; Original Research; Rectal Cancer; Surgeons; Surgery; Systematic review; Transanal TME; Treatment outcome; Poland; laparoscopic TME; transanal TME; low rectal cancer; minimally invasive surgery; rectal cancer
• ISSN: 1179-1322; 1179-1322
• DOI: 10.2147/CMAR.S181214

Transanal total mesorectal excision (TaTME) is emerging as a novel alternative to laparoscopic total mesorectal excision (LaTME). The aim of this study was to compare clinical and pathological results from these two techniques in patients undergoing rectal resections because of low rectal cancer. Thirty-five patients undergoing TaTME were matched with 35 patients operated on using LaTME. Composite primary endpoint (complete TME, negative circumferential resection margin [pCRM], and distal resection margin [pDRM]) was used to assess pathological quality specimens. Secondary outcomes included operative and postoperative parameters (operative time, total blood loss, postoperative morbidity, length of stay, 30-day mortality). Composite primary endpoint was achieved by 85% of subjects in the TaTME group and 82% of subjects in the LaTME group ( =0.66). Mean pCRM was 1.1±1.29 vs 0.99±0.78 mm ( =0.25). Distal pDRM was 1.57±0.92 and 1.98±1.22 cm ( =0.15). In the TaTME and LaTME groups, respectively, complete mesorectal excision was achieved in 89% and 83% of subjects, while excision was nearly complete for the remaining 11% and 17% ( =0.23). TaTME appears to be a noninferior alternative to laparoscopic surgery. TaTME allows for quality retrieval of surgical specimens with comparable clinical outcomes with LaTME.