Impact of Platelet Count in Retinopathy of Prematurity

• Published in: Turk oftalmoloji gazetesi Vol. 50; no. 6; pp. 351 - 355
• Main Authors: Keskek, Nedime Sahinoglu, Gulcan, Hande, Yilmaz, Gursel, Akkoyun, Imren
• Format: Journal Article
• Language: English
• Published: Turkey Galenos Yayinevi Tic. Ltd 29.12.2020; Türk Oftalmoloji Derneği; Galenos Publishing; Galenos Yayinevi
• Subjects: Analysis; Birth Weight; Blood Platelets - pathology; Female; Gestational Age; Humans; Infant, Newborn; Infants; Male; Medical research; Medicine, Experimental; Original; platelet; Platelet Count; Prognosis; retinopathy of prematurity; Retinopathy of Prematurity - blood; Retinopathy of Prematurity - diagnosis; Retrolental fibroplasia; Retrospective Studies; Risk Factors; Tıp; İstanbul; Türkiye; retinopathy of prematurity, risk factors; platelet; Birth weight; gestational age; risk factors; retinopathy of prematurity
• ISSN: 1300-0659; 2149-8695; 2149-8709; 2147-2661
• DOI: 10.4274/tjo.galenos.2020.01058

The aim of the study was to investigate the risk factors for retinopathy of prematurity (ROP), including platelet count. This retrospective study analyzed 137 infants in 3 subgroups: no ROP; mild ROP, and severe ROP requiring laser treatment (type 1 ROP). A retrospective review of records was performed and statistical analysis of possible risk factors for ROP including platelet count was evaluated by using logistic regression. Birth weight (BW), gestational age (GA), and low platelet count in the first week after birth were significant risk factors for developing ROP (p=0.038, 0.02, and 0.004, respectively). BW, GA, ventilation, and lower platelet count were associated with progression to type 1 ROP (p=0.004; 0.027, and 0.021, respectively). Lower platelet count in the first week after birth is a risk factor for ROP development in addition to the previously established factors of ventilation need, low BW, and low GA.